Melatonin's Role in Hair Follicle Growth and Development: A Cashmere Goat Perspective

    Zibin Zheng, Zhenyu Su, Wei Zhang
    Studysummary This review explores melatonin's role in hair follicle cycles and its molecular mechanisms that enhance antioxidant capacity and modulate gene expression, offering potential strategies to improve cashmere production and treating human alopecia, according to the authors.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 36

    1. Melatonin Promotes Proliferation of Inner Mongolia Cashmere Goat Hair Follicle Papilla Cells Through Wnt10b Genomics · 2024
    2. Melatonin Regulates the Periodic Growth of Secondary Hair Follicles Through the Nuclear Receptor RORα Frontiers in Veterinary Science · 2023
    3. MicroRNA-205 Promotes Hair Regeneration by Modulating Mechanical Properties of Hair Follicle Stem Cells Proceedings of the National Academy of Sciences · 2023
    4. Melatonin Promotes the Development of Secondary Hair Follicles by Regulating circMPP5 Journal of Animal Science and Biotechnology · 2023
    5. Hair Follicle Development and Cashmere Traits in Albas Goat Kids Animals · 2023
    6. The Developmental Basis of Fingerprint Pattern Formation and Variation Cell · 2023
    7. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1 International Journal of Molecular Sciences · 2023
    8. Insights Into Male Androgenetic Alopecia Using Comparative Transcriptome Profiling: Hypoxia-Inducible Factor-1 and Wnt/Beta-Catenin Signalling Pathways British Journal of Dermatology · 2022
    9. Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA Frontiers in Veterinary Science · 2022
    10. Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus BMC Genomics · 2022
    11. Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective Journal of pineal research · 2022
    12. Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway Frontiers in Cell and Developmental Biology · 2021
    13. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    14. Effects of Melatonin Administration to Cashmere Goats on Cashmere Production and Hair Follicle Characteristics in Two Consecutive Cashmere Growth Cycles Domestic Animal Endocrinology · 2020
    15. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    16. The Effects of Extended Photoperiod and Warmth on Hair Growth in Ponies and Horses at Different Times of Year PloS one · 2020
    17. Effect of Melatonin Administration to Lactating Cashmere Goats on Milk Production of Dams and Hair Follicle Development in Their Offspring Animal · 2019
    18. Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis Journal of Pineal Research · 2019
    19. Melatonin Promotes Cashmere Goat (Capra Hircus) Secondary Hair Follicle Growth: A View from Integrated Analysis of Long Non-Coding and Coding RNAs Cell Cycle · 2018
    20. The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo Journal of Investigative Dermatology · 2016
    21. Expression of the RORα Gene in Inner Mongolian Cashmere Goat Hair Follicles Genetics and molecular research · 2015
    22. Hoxc13/β-Catenin Correlation with Hair Follicle Activity in Cashmere Goat Journal of integrative agriculture/Journal of Integrative Agriculture · 2012
    23. Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro British Journal of Dermatology · 2010
    24. Characterization of BMP2 Gene Expression in Embryonic and Adult Inner Mongolia Cashmere Goat (Capra Hircus) Hair Follicles Canadian Journal of Animal Science · 2009
    25. Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control ˜The œFASEB journal · 2009
    26. Melatonin in the Skin: Synthesis, Metabolism, and Functions Trends in Endocrinology and Metabolism · 2008
    27. Melatonin and the Hair Follicle Journal of pineal research · 2007
    28. Scratching the Surface of Skin Development Nature · 2007
    29. The Hair Cycle Journal of Cell Science · 2006
    30. The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors ˜The œFASEB journal · 2005
    31. On the Role of Melatonin in Skin Physiology and Pathology Endocrine journal · 2005
    32. Serotoninergic And Melatoninergic Systems Are Fully Expressed In Human Skin ˜The œFASEB journal · 2002
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    34. The Localization and Characterization of Insulin-Like Growth Factor-I Receptors and the Investigation of Melatonin Receptors on the Hair Follicles of Seasonal and Non-Seasonal Fiber-Producing Goats Journal of Endocrinology/Journal of endocrinology · 1996
    35. The Effect of Melatonin Implants Administered from December Until April on Plasma Prolactin, Triiodothyronine, and Thyroxine Concentrations and on the Timing of the Spring Moult in Cashmere Goats Animal Science/Animal science · 1995
    36. Murine Skin as a Target for Melatonin Bioregulation Experimental dermatology · 1994

    Related research 7

    1. Single-Cell Sequencing Reveals the New Existence Form of Dermal Papilla Cells in the Hair Follicle Regeneration of Cashmere Goats Genomics · 2022
    2. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    3. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Hair Follicle Cycling in Cashmere Goats Research Square (Research Square) · 2019
    4. Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus) Genetics and molecular research · 2015
    5. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
    6. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    7. Hoxc13/β-Catenin Correlation with Hair Follicle Activity in Cashmere Goat Journal of integrative agriculture/Journal of Integrative Agriculture · 2012