TLDR Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.
In a study involving 24 female Inner Mongolian Cashmere goats, melatonin treatment was found to improve cashmere production during the first growth cycle after administration, with treated goats showing an 18% increase in fleece weight, longer staple length by 1.57 cm, finer fiber diameter by 0.81 um, and 15% greater fiber density compared to the control group. However, these effects did not persist into the second growth cycle. Melatonin did not alter the total number of secondary hair follicles but did advance their onset of activity by two months and increased the number of active follicles in the first cycle. The study concluded that melatonin's benefits are limited to the cycle in which it is administered, with no lasting effects on subsequent cycles, which could be advantageous for the cashmere goat industry. The study involved 12 goats in the melatonin-treated group and 12 in the control group.
46 citations
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March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
32 citations
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May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
5 citations
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October 2011 in “Small ruminant research” Goat hair growth and follicle activity change with the seasons and differ between males and females.
10 citations
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June 2005 in “Small ruminant research” Melatonin treatment may increase cashmere production in Spanish goats.
2 citations
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February 2022 in “Genomics” Researchers discovered new cell types in goat hair follicles that could help understand hair regrowth and human hair loss.
8 citations
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July 2020 in “BMC genomics” The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
1 citations
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August 2019 in “Research Square (Research Square)” Cashmere goats have a hair growth cycle with specific genes regulating growth, regression, and resting periods.
14 citations
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January 2015 in “Genetics and molecular research” The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
61 citations
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April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
22 citations
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July 2012 in “Journal of integrative agriculture/Journal of Integrative Agriculture” Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.