Functional Hair Follicle Regeneration: An Updated Review

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

PI3K/Akt pathway is crucial for hair growth and regeneration.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

Injected cells show potential for hair growth.

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

Nanofiber structure helps regenerate hair follicles.

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

Human placenta hydrogel helps restore cells needed for hair growth.

Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.

Researchers found a way to turn skin cells into cells that can grow new hair.

Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.

Created material boosts hair growth and kills bacteria for wound healing.

Trichostatin A helps restore hair-growing ability in skin cells used for hair regeneration.

BMP6 and Wnt10b control whether hair follicles are resting or growing.

Cattle skin has leptin which might control skin and hair growth.

Researchers created human hair follicles using a new method that could help treat hair loss.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Hoxc genes control hair growth through Wnt signaling.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

NF-κB is crucial for different stages and types of hair growth in mice.

The document concludes that skin-derived precursors can be grown and may help in hair growth and skin repair.

A form of vitamin E promotes hair growth by activating a specific skin pathway.

The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.

Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Icariin helps mouse hair grow by boosting a growth factor in skin cells.

Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.

Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.

STAT5 activation is crucial for starting the hair growth phase.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

Boosting β-catenin signaling in certain skin cells can enhance hair growth.

EGFR helps mouse hair follicles stop growing by reducing certain growth regulators.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Blocking JAK-STAT signaling can lead to hair growth.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Leptin helps start the growth phase of hair.

Researchers made stem cells from human hair follicle cells with higher efficiency than from skin cells.

Leptin, a hormone, is important for starting hair growth.

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

Human stem cells can help form hair follicles in mice.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.

The gene HDC is important for the development of hair follicles in newborn mice.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Forming spheres boosts the ability of certain human cells to create hair follicles when mixed with mouse skin cells.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

EVAL membranes help create cell structures that can regrow hair follicles.

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.

Notch signalling helps skin cells differentiate and prevents tumors.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.

The study found that higher levels of ET-1 and SCF in early-stage dermal papilla cells improve their ability to regenerate hair follicles.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Cultured epithelium can form hair follicles when combined with dermal papillae.

Hair follicle stem cells can form both hair follicles and skin.

Hair papilla cells can create and regenerate hair bulbs under the right conditions.

Human hair follicles can regenerate after removal, but with low success rate.