PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration

    April 2020 in “ Stem Cell Research & Therapy
    Yu Chen, Zhimeng Fan, Xiaoxiao Wang, Miaohua Mo, Shu Bin Zeng, Ren-He Xu, Xusheng Wang, Yaojiong Wu
    Image of study
    TLDR PI3K/Akt pathway is crucial for hair growth and regeneration.
    A study published in Stem Cell Research & Therapy found that the PI3K/Akt signaling pathway is essential for de novo hair follicle regeneration. The study used epidermal stem cells and skin-derived precursors from mice to investigate the molecular mechanisms of hair follicle regeneration. The researchers found that inhibiting the PI3K/Akt pathway significantly suppressed regeneration and identified it as crucial for the process. The study suggests potential therapeutic applications for enhancing hair regeneration. Platelet-rich plasma (PRP) may also promote hair regrowth by activating quiescent hair follicle stem cells to proliferate.
    Discuss this study in the Community →

    Research cited in this study

    24 / 24 results

    Related Community Posts Join

    3 / 3 results

    Related Research

    5 / 5 results