Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration

    June 2012 in “ Nature ”
    Panteleimon Rompolas, Elizabeth R. Deschene, Giovanni Battista Zito … Valentina Greco
    Studysummary This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.
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    Research cited in this study 5

    1. TCF/Lef1 Activity Controls Establishment of Diverse Stem and Progenitor Cell Compartments in Mouse Epidermis The EMBO Journal · 2011
    2. Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches? Development · 2010
    3. Epidermal Stem Cell Diversity and Quiescence EMBO molecular medicine · 2009
    4. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    5. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001

    Related research 6

    1. Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing Frontiers in Medicine · 2022
    2. Hair Follicle Regeneration In Vitro Paleontological Journal · 2016
    3. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    4. Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis Genes & development · 2010
    5. The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair Science · 2009
    6. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003