Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives

    September 2011 in “ Tissue Engineering Part B-reviews ”
    Seyed Babak Mahjour, Fariborz Ghaffarpasand, Hongjun Wang
    Studysummary This report reviews current advances in hair follicle regeneration for tissue-engineered skin grafts and highlights the feasibility and challenges of creating human hair follicles in this setting, suggesting key bioengineering requirements.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 29

    1. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    2. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    3. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    4. Hair Morphogenesis In Vitro: Formation of Hair Structures Suitable for Implantation Regenerative Medicine · 2008
    5. Preparation of Scaffolds from Human Hair Proteins for Tissue-Engineering Applications Biomedical Materials · 2008
    6. Isolation and Short-Term Culture of Primary Keratinocytes, Hair Follicle Populations, and Dermal Cells from Newborn Mice and Keratinocytes from Adult Mice for In Vitro Analysis and Grafting to Immunodeficient Mice Nature Protocols · 2008
    7. Defining Hair Follicles in the Age of Stem Cell Bioengineering Journal of Investigative Dermatology · 2007
    8. Hair Follicle Regeneration Using Grafted Rodent and Human Cells Journal of Investigative Dermatology · 2007
    9. Hair Follicle Reformation Induced by Dermal Papilla Cells from Human Scalp Skin Archives of Dermatological Research · 2006
    10. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    11. The Hair Growth Promoting Effect of Ascorbic Acid 2-Phosphate, a Long-Acting Vitamin C Derivative Journal of Dermatological Science · 2006
    12. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    13. Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling Proceedings of the National Academy of Sciences of the United States of America · 2005
    14. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005
    15. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    16. Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common? Differentiation · 2004
    17. Dermal Papilla-Induced Hair Differentiation of Adult Epithelial Stem Cells from Human Skin Physiological Genomics · 2004
    18. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    19. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004
    20. Cell Movement in the Hair Follicle Dermis: More Than a Two-Way Street? Journal of Investigative Dermatology · 2003
    21. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    22. Overexpression Of Sonic Hedgehog Suppresses Embryonic Hair Follicle Morphogenesis Developmental Biology · 2003
    23. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    24. Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance Dermatologic clinics · 1996
    25. Outer Root Sheath Cells Organize Into Epidermoid Cyst-Like Spheroids When Cultured Inside Matrigel: A Light-Microscopic and Immunohistological Comparison Between Human ORS Cells and Interfollicular Keratinocytes Cell and Tissue Research · 1994
    26. Organotypic Cocultures as Models to Study Cell-Cell and Cell-Matrix Interactions of Human Hair Follicle Cells Skin Pharmacology and Physiology · 1994
    27. An Efficient Method for Isolation of Hair Papillae and Follicle Epithelium from Human Scalp Specimens British journal of dermatology/British journal of dermatology, Supplement · 1993
    28. Dermal-Epidermal Interactions: Follicle Derived Cell Populations in the Study of Hair Growth Mechanisms ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    29. Improved Method for the Isolation and Cultivation of Human Scalp Dermal Papilla Cells Journal of Investigative Dermatology · 1992

    Related research 4

    1. Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration British journal of dermatology/British journal of dermatology, Supplement · 2017
    2. Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures Biomaterials · 2016
    3. Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives Tissue Engineering Part B-reviews · 2011
    4. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010