Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model

    James M. Waters, Jessica E. Lindo, Ruth M. Arkell, Allison J. Cowin
    Studysummary This study found that higher levels of the protein Flii were associated with enhanced hair follicle regeneration and longer hair fibers in a mouse model.
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    Research cited in this study 9

    1. Epidermal Stem Cell Diversity and Quiescence EMBO molecular medicine · 2009
    2. Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth Journal of Investigative Dermatology · 2008
    3. Keratin 17 Modulates Hair Follicle Cycling in a TNFα-Dependent Fashion Genes & Development · 2006
    4. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor Alpha Is Checked by ER Beta Signaling Endocrinology · 2005
    5. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development The Journal of Cell Biology · 1998
    6. Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse Journal of Investigative Dermatology · 1996
    7. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    8. Cellular and Extracellular Involvement in the Regeneration of the Rat Lower Vibrissa Follicle Development · 1992
    9. Hair Growth Inhibition by Heparin in Mice: A Model System for Studying the Modulation of Epithelial Cell Growth by Glycosaminoglycans British Journal of Dermatology · 1991

    Related research 5

    1. Through the Lens of Hair Follicle Neogenesis: A New Focus on Mechanisms of Skin Regeneration After Wounding Seminars in Cell & Developmental Biology · 2019
    2. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    3. The Influence of Flightless I: Regeneration Versus Wound Healing Journal of Investigative Dermatology · 2011
    4. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    5. Expression of Keratin 15 in Alopecia's Frontal Hair Follicle Zhongguo linchuang yixue · 2007