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Glossary Nerve Regeneration

process where damaged neurons repair and restore their function

Nerve regeneration, also known as nerve repair or neural regeneration, is the process by which damaged nerve cells (neurons) repair themselves and restore their function. This involves the regrowth of axons, the long thread-like parts of neurons, and the re-establishment of connections with other neurons or target tissues. While peripheral nerves have some capacity for regeneration, central nervous system nerves (like those in the brain and spinal cord) have limited ability to heal, making research in this area crucial for treating injuries and neurodegenerative diseases.

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Research

5 / 1000+ results

research Plasticity of epithelial stem cells in tissue regeneration

479 citations , June 2014 in “Science”

This review discusses the plasticity of epithelial stem cells in regenerative contexts and reports no new research findings; the authors highlight potential implications for regenerative medicine and cancer.

research Skin shedding and tissue regeneration in African spiny mice (Acomys)

418 citations , September 2012 in “Nature”

This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.

research The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair

295 citations , June 2009 in “Science”

This article reviews the role of stromal stem cells in mammalian wound repair, suggesting they may perform functions similar to blastemal cells in simpler organisms, but reports no new experimental results.

research Nerve dependence in tissue, organ, and appendage regeneration

228 citations , September 2012 in “Trends in Neurosciences”

This review examines the role of nerves in regeneration across various species and discusses their importance as components in the progenitor cell niche, reporting no new clinical results.

research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration

220 citations , March 2020 in “Advanced functional materials”

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

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Community Join

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community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

5 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for treating alopecia and wound healing. They enhance cell viability, maintain stemness, and promote hair and tissue regeneration without teratoma formation.

community How Does Exosome Therapy Work for Hair Loss?

in Research/Science 5 upvotes 2 years ago

Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

community Topical Metformin for Hair Transplant donor area skin/hair regeneration?

4 upvotes 1 year ago

Topical Metformin shows potential for regenerating hair follicles and minimizing scarring in hair transplant donor areas, similar to Verteporfin but without its side effects. The discussion suggests considering Metformin for post-hair transplant care, though more human trials are needed.

community Update and new paper from Dr tsuji

26 upvotes 7 years ago

Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.

10 upvotes 3 years ago

Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for alopecia treatment. They enhance cell viability, maintain stemness, and induce hair growth without teratoma formation.

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Learn

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learn Verteporfin

chemical that might completely regrow follicles from hair transplant extractions

What is Verteporfin, and why is it being studied for hair follicle regeneration? Verteporfin is being studied for hair follicle regeneration due to its ability to inhibit YAP, promoting tissue healing.

learn Thymosin Beta 4

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

learn Beta Polypeptide

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

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Clinics

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