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Glossary Pluripotency

ability to become nearly any cell type in the body

Pluripotency refers to the ability of a stem cell to develop into almost any type of cell in the body. This means that pluripotent stem cells can give rise to various cell types, such as skin cells, nerve cells, or blood cells, making them incredibly valuable for medical research and regenerative medicine.

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Research

5 / 1000+ results

research Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes

160 citations , January 2017 in “Development”

This study found that hypertrophic chondrocytes at the fracture callus border may convert to osteoblasts, influenced by vasculature and pluripotency gene expression.

research Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy

28 citations , January 2023 in “Cell Transplantation”

This study found that the Hy-Tissue Nanofat product isolates a significant number of proliferative nucleated cells and shows potential for regenerative medicine due to its rich content of adipose-derived stem cells and pluripotent MUSE cells.

research Reprogramming of Human Hair Follicle Dermal Papilla Cells into Induced Pluripotent Stem Cells

26 citations , February 2012 in “Journal of Investigative Dermatology”

This study found that dermal papilla cells from human hair follicles can be reprogrammed into induced pluripotent stem cells, but their efficiency is similar to that of fibroblasts, unlike in mice.

research Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning

18 citations , November 2016 in “PeerJ”

This study found that hair follicles can be used to generate pluripotent stem cells, which successfully differentiate into keratinocytes and may improve hair regeneration and grafting for medical applications.

research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway

11 citations , June 2021 in “Frontiers in Cell and Developmental Biology”

This study found that melatonin may enhance goat cashmere growth by activating Wnt signaling and regulating stem cell pluripotency through mechanisms involving NOGGIN and BMP4 pathways.

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community Hair and normal skin created from human pluripotent stem cells for the first time

86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

community Functional hair follicles grown from stem cells: Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

171 upvotes 7 years ago

Scientists have grown natural-looking hair from stem cells, potentially revolutionizing hair growth treatments. Concerns include cost, DHT resistance, and the need for future procedures.

community Anyone hear about Stemson's presentation at the 2021 Global Hair Loss Summit?

7 upvotes 4 years ago

Stemson's presentation discussed using induced pluripotent stem cell technology to create new hair follicles for treating hair loss. The conversation also mentions treatments like Minoxidil, finasteride, and RU58841.

community Hair Multiplication Projects in China - Promising clinical trial results on Mice

34 upvotes 1 year ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

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