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    Glossary transdifferentiation

    mature cell changes directly into another mature cell type

    Transdifferentiation is a biological process where one type of mature cell transforms into another type of mature cell without first reverting to a stem cell state. For example, a skin cell might change directly into a nerve cell. This process is significant in regenerative medicine and tissue engineering because it offers potential for repairing damaged tissues and organs.

    Research 10 of 444

    1. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    2. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. The International Journal of Developmental Biology · 2004 · 55 citations
    3. Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4 Stem cells international · 2015 · 15 citations
    4. Transdifferentiation of rat hair follicle stem cells to epithelium-like cells induced by stroma of limbus corneae Di-san junyi daxue xuebao · 2008
    5. Phloem transdifferentiation from immature xylem cells during bark regeneration after girdling in Eucommia ulmoides Oliv Journal of Experimental Botany · 2008 · 44 citations
    6. Retinoic Acid-Induced Epidermal Transdifferentiation in Skin Journal of developmental biology · 2014 · 1 citations
    7. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    8. Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1 Cell Biology International · 2009 · 20 citations
    9. Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells Development · 2024 · 4 citations
    10. Limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial‐like cells Acta Ophthalmologica · 2008
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