Molecular Principles of Hair Follicle Induction and Morphogenesis

    January 2005 in “ BioEssays ”
    Ruth Schmidt‐Ullrich, Ralf Paus
    Studysummary This review introduces the morphological and molecular principles of hair follicle development but reports no new experimental results, focusing on recent insights and forming a working hypothesis.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 28

    1. Regulating the Regulators: Routing the Wnt-Beta-Catenin-Lef Signals Journal of Investigative Dermatology · 2004
    2. Making Waves with Hairs: Genetic and Epigenetic Factors in Hair Pattern Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    3. Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency Molecular and Cellular Biology · 2004
    4. Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models ˜The œInternational journal of developmental biology · 2004
    5. Epithelial Growth Control by Neurotrophins: Leads and Lessons from the Hair Follicle Progress in brain research · 2004
    6. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    7. Stimulation of Ectodermal Organ Development by Ectodysplasin-A1 Developmental Biology · 2003
    8. Hox in Hair Growth and Development Die Naturwissenschaften · 2003
    9. Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin The FASEB Journal · 2003
    10. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003
    11. Cyclic Alopecia in Msx2 Mutants: Defects in Hair Cycling and Hair Shaft Differentiation Development · 2002
    12. Developmental Timing of Hair Follicle and Dorsal Skin Innervation in Mice Journal of comparative neurology · 2002
    13. The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling ˜The œAmerican journal of pathology · 2002
    14. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002
    15. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    16. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    17. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
    18. The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle Genes & development · 2001
    19. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    20. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001
    21. Edar/Eda Interactions Regulate Enamel Knot Formation in Tooth Morphogenesis Development · 2000
    22. Msx2 Deficiency in Mice Causes Pleiotropic Defects in Bone Growth and Ectodermal Organ Formation Nature genetics · 2000
    23. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    24. Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair EMBO journal · 1999
    25. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    26. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    27. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools Medical Entomology and Zoology · 1994
    28. Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis Developmental dynamics · 1994

    Related research 1

    1. Interrogating the Integument: The Role of the Epidermis in Hair Induction Experimental dermatology · 2014