Epithelial Growth Control by Neurotrophins: Leads and Lessons from the Hair Follicle

    January 2004 in “ Progress in brain research ”
    Vladimir A. Botchkarev, Natalia V. Botchkareva, Eva M.J. Peters, Ralf Paus
    Studysummary This review examines the role of neurotrophins in hair follicle development and remodeling, highlighting potential therapeutic applications for hair growth disorders, but it reports no new empirical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 14

    1. P75 Neurotrophin Receptor Antagonist Retards Apoptosis-Driven Hair Follicle Involution (Catagen) Journal of Investigative Dermatology · 2003
    2. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003
    3. Developmental Timing of Hair Follicle and Dorsal Skin Innervation in Mice Journal of comparative neurology · 2002
    4. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    5. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    6. Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin and Hair Growth Modulation by Neuropeptides Journal of Investigative Dermatology · 2001
    7. A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression The FASEB Journal · 2000
    8. Retardation of Hair Follicle Development by the Deletion of TrkC, High-Affinity Neurotrophin-3 Receptor Journal of Investigative Dermatology · 1999
    9. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    10. Splitting Hairs: Molecular Mechanisms of Hair and Feather Development Cell · 1998
    11. A Simple Immunofluorescence Technique for Simultaneous Visualization of Mast Cells and Nerve Fibers Reveals Selectivity and Hair Cycle-Dependent Changes in Mast Cell-Nerve Fiber Contacts in Murine Skin Archives of Dermatological Research · 1997
    12. Neural Mechanisms of Hair Growth Control Journal of Investigative Dermatology Symposium Proceedings · 1997
    13. Apoptosis in Human Skin Development: Morphogenesis, Periderm, and Stem Cells Developmental dynamics · 1994
    14. Synthesis of Nerve Growth Factor mRNA in Cultures of Developing Mouse Whisker Pad, a Peripheral Target Tissue of Sensory Trigeminal Neurons The Journal of Cell Biology · 1993