Brain-Derived Nerve Factor and Neurotrophins in Androgenetic Alopecia

July 2011 in “ British Journal of Dermatology ”

Ratchathorn Panchaprateep, Wiwat Korkij, Pravit Asawanonda

androgenetic alopecia brain-derived nerve factor neurotrophins cytokines vascular endothelial growth factor AGA BDNF VEGF

TLDR Lower growth factors linked to balding in androgenetic alopecia.

This study compared the levels of growth factors and cytokines in balding and non-balding scalp specimens from individuals with androgenetic alopecia (AGA). The results suggest that brain-derived nerve factor (BDNF) and neurotrophins may be involved in the balding pattern observed in AGA. The study also found a significant downregulation of cytokines in the vascular endothelial growth factor family in balding scalp. The study provides a basis for future research on therapeutic interventions for AGA.

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