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GlossaryBrain-Derived Neurotrophic Factor (BDNF)

protein supporting neuron growth and survival in the brain

Brain-Derived Neurotrophic Factor (BDNF) is a protein that plays a crucial role in the growth, maintenance, and survival of neurons in the brain. It is essential for cognitive functions such as learning and memory, and it also supports the health of existing neurons while encouraging the growth of new ones.

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research Female Pattern Hair Loss and Negative Psychological Impact: Possible Role of Brain-Derived Neurotrophic Factor

July 2023 in “Dermatology practical & conceptual”

Women with Female Pattern Hair Loss may experience more stress, anxiety, and depression, and have lower levels of BDNF, which could predict the psychological impact.

research Gene Polymorphisms and Serum Levels of BDNF and CRH in Vitiligo Patients

July 2022 in “PLOS ONE”

Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

research Investigating the Synergic Effects of Valproic Acid and Crocin on BDNF and GDNF Expression in Epidermal Neural Crest Stem Cells

10 citations , January 2020 in “Acta Neurobiologiae Experimentalis”

Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression

research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression

64 citations , March 2005 in “Journal of Investigative Dermatology”

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

research Evaluation of Serum Brain-Derived Neurotrophic Factor to Assess the Association Between Psoriasis and Depression

2 citations , September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.

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community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 2 years ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community Is anyone taking creatine while on fin and/or dut?

in Finasteride/Dutasteride 33 upvotes 1 year ago

The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Stop Complaining about Creatine. You're just fixated on shedding.

in Research/Science 76 upvotes 6 months ago

Creatine is unlikely to cause hair loss as it does not raise DHT levels. Hair loss is more likely due to genetics, medications, or lifestyle changes.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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