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This study found that brain-derived nerve factor protein expression was significantly increased in balding scalp samples from men with androgenetic alopecia, suggesting it may play a role in hair follicle regulation.

This study found that neurotrophins produced by balding dermal papilla cells inhibited both their proliferation and hair follicle growth in vitro, suggesting a potential role in androgenetic alopecia.

In this study, patients with androgenetic alopecia experiencing stress had higher cortisol levels and altered neurotrophic factors compared to non-stressed patients, which correlated with more severe hair loss progression even after minoxidil treatment.

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.

This study found that sensory and sympathetic innervation in the mystacial pads of mice is governed by a balance of neurotrophin signaling, highlighting the roles of NGF/trkA and NT-3/trkC pathways.