A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression

    October 2000 in “ The FASEB Journal ”
    Vladimir A. Botchkarev, Natalia V. Botchkareva, Kathryn M. Albers … Ralf Paus
    Studysummary In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.
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    Research cited in this study 13

    1. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    2. The Role of the Hairless (Hr) Gene in the Regulation of Hair Follicle Catagen Transformation American Journal Of Pathology · 1999
    3. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro Journal of Investigative Dermatology · 1998
    4. Towards Defining the Pathogenesis of the Hairless Phenotype Journal of Investigative Dermatology · 1998
    5. Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    6. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    7. Immunohistochemical Analysis of Tissue Remodeling During the Anagen-Catagen Transition of the Human Hair Follicle British Journal of Dermatology · 1997
    8. A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A Journal of Investigative Dermatology · 1994
    9. Human Hair Growth In Vitro: A Model for the Study of Hair Follicle Biology Journal of Dermatological Science · 1994
    10. Expression of the Bcl-2 Proto-Oncogene in the Cycling Adult Mouse Hair Follicle Journal of Investigative Dermatology · 1994
    11. The Secret Life of the Hair Follicle Trends in genetics · 1992
    12. Morphogenesis of the Hair Follicle During Catagen Cell and Tissue Research · 1970
    13. Growth of the Hair Physiological Reviews · 1954

    Related research 2

    1. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression Journal of Investigative Dermatology · 2005
    2. A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression The FASEB Journal · 2000