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    Glossary p75 neurotrophin receptor

    protein on cell surfaces regulating survival and apoptosis

    The p75 neurotrophin receptor (p75NTR) is a protein found on the surface of certain cells, including neurons and hair follicle cells. It plays a crucial role in regulating cell survival, growth, and apoptosis (programmed cell death) by binding to neurotrophins, which are a family of proteins that promote the survival and function of neurons. This receptor is significant in both the development of the nervous system and in conditions like alopecia, where it can influence hair follicle health and regeneration.

    Research 10 of 206

    1. A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression The FASEB Journal · 2000 · 96 citations
    2. p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen) Journal of Investigative Dermatology · 2003 · 24 citations
    3. [Construction and identification of mouse model with conditional knockout of p75 neurotrophin receptor gene in epidermal cells by Cre-loxP system]. PubMed · 2019 · 1 citations
    4. ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators Experimental dermatology · 2006
    5. Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro Molecular Medicine Reports · 2017 · 5 citations
    6. Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. PubMed · 1998 · 122 citations
    7. Inhibitory Effects of Polyacetylene Compounds from <i>Panax ginseng</i> on Neurotrophin Receptor-Mediated Hair Growth Biological & Pharmaceutical Bulletin · 2017 · 7 citations
    8. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    9. Retardation of Hair Follicle Development by the Deletion of TrkC, High-Affinity Neurotrophin-3 Receptor Journal of Investigative Dermatology · 1999 · 14 citations
    10. Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection Allergo Journal · 2000 · 7 citations
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