TLDR Hair follicles create different cell layers and proteins, controlled by various molecules.
The mammalian hair follicle, composed of uniform epithelial and mesenchymal cells, was found to produce multiple concentric cylinders of distinct cell types, each synthesizing unique proteins. Evidence suggested that various growth factors, cell adhesion molecules, and other molecules played crucial roles in regulating this complex organ.
13 citations,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
9 citations,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
42 citations,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
