TLDR Hair follicles create different cell layers and proteins, controlled by various molecules.
The mammalian hair follicle, composed of uniform epithelial and mesenchymal cells, was found to produce multiple concentric cylinders of distinct cell types, each synthesizing unique proteins. Evidence suggested that various growth factors, cell adhesion molecules, and other molecules played crucial roles in regulating this complex organ.
13 citations,
December 1983 in “Canadian journal of zoology” Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
9 citations,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
3 citations,
April 2018 in “Therapeutic Delivery” Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.
5 citations,
January 2021 in “Frontiers in Cell and Developmental Biology” Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.
