Engineering the Future of Hair Follicle Regeneration and Delivery

April 2018 in “ Therapeutic Delivery ”

Justin Tan, Lifeng Kang

hair follicle regeneration tissue engineering dermal papilla cells epithelial influences hair follicular cell composites hair reconstitution in vivo molecular events cellular events hair follicle development

TLDR Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.

This article discusses the limitations of current hair loss treatments and explores tissue engineering technologies for hair follicle regeneration and delivery. The document highlights the importance of restoring epithelial influences on dermal papilla cells and the positional relationships of hair follicular cell composites. The article also discusses various methods for delivering follicular cells for hair reconstitution in vivo. The conclusion emphasizes the complexity of designing hair follicle regeneration and delivery due to the tightly regulated molecular and cellular events involved in hair follicle development.

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Research cited in this study

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83 citations , January 2015 in “World Journal of Stem Cells”

Hair follicle regeneration needs special conditions and young cells.

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40 citations , June 2013 in “Biomaterials”

Scientists created 3D hair-like structures that could help study hair growth and test treatments.

Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells

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Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.

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Follicular unit hair transplantation is the standard method for natural-looking hair restoration in androgenic alopecia.

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