Self-Assembly of Dermal Papilla Cells into Inductive Spheroidal Microtissues on Poly(Ethylene-Co-Vinyl Alcohol) Membranes for Hair Follicle Regeneration
June 2008
in “
Biomaterials
”
Studysummary This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This 14-year-old study explores the use of poly(ethylene-co-vinyl alcohol) (EVAL) membranes as a substrate for the self-assembly of dermal papilla cells (DPCs) into inductive spheroidal microtissues for hair follicle regeneration. The researchers found that EVAL membranes supported the formation of DPC microtissues with high viability and proliferation rates, and that these microtissues were able to induce hair follicle formation in vivo. The study suggests that EVAL membranes may be a promising substrate for hair follicle regeneration.