A Simple and Rapid Model for Hair-Follicle Regeneration in the Nude Mouse

In 2015, researchers developed an Improved Flap Model (IFM) for hair regeneration in nude mice, which was more efficient and less invasive than the traditional flap assay. The IFM produced a large number of normal hairs in 20.67 ± 0.67 days, compared to 29.33 ± 0.67 days with the traditional method. The researchers believed the increased blood supply at the transplantation sites contributed to the faster hair regeneration. The success rate for hair reconstitution was 100% for both methods, but the IFM was faster, making it a more efficient method. The study involved 6 mice per group.