A Simple and Rapid Model for Hair-Follicle Regeneration in the Nude Mouse

    January 2015 in “ Clinical and Experimental Dermatology ”
    Yan-Kuin Su, Yuxin Miao, Jiechao Jiang, Hongfang Liu, J. F. Hu, Zhen Hu
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    TLDR A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.
    In 2015, researchers developed an Improved Flap Model (IFM) for hair regeneration in nude mice, which was more efficient and less invasive than the traditional flap assay. The IFM produced a large number of normal hairs in 20.67 ± 0.67 days, compared to 29.33 ± 0.67 days with the traditional method. The researchers believed the increased blood supply at the transplantation sites contributed to the faster hair regeneration. The success rate for hair reconstitution was 100% for both methods, but the IFM was faster, making it a more efficient method. The study involved 6 mice per group.
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