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    Dynamic Signals for Hair Follicle Development and Regeneration

    July 2011 in “ Stem Cells and Development ”
    Xusheng Wang, Edward E. Tredget, Yaojiong Wu
    Studysummary This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 45

    1. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    2. APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex Nature · 2010
    3. Clock Genes, Hair Growth, and Aging Aging · 2010
    4. Fine Mapping of the Human AR/EDA2R Locus in Androgenetic Alopecia British Journal of Dermatology · 2010
    5. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    6. Hair Follicle Neogenesis Induced by Cultured Human Scalp Dermal Papilla Cells Regenerative Medicine · 2009
    7. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009
    8. Akt2 and SGK3 Are Both Determinants of Postnatal Hair Follicle Development The FASEB Journal · 2009
    9. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    10. Embryonic Hair Follicle Fate Change by Augmented Beta-Catenin Through Shh and Bmp Signaling Development · 2009
    11. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    12. Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling Development · 2008
    13. Heparanase 1: A Key Participant of Inner Root Sheath Differentiation Program and Hair Follicle Homeostasis Experimental Dermatology · 2008
    14. Beyond Wavy Hairs: The Role of EGFR in Skin and Hair Biology American Journal Of Pathology · 2008
    15. Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes Developmental biology · 2008
    16. EDA2R Is Associated With Androgenetic Alopecia Journal of Investigative Dermatology · 2008
    17. Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit During Hair Cycle Acta histochemica et cytochemica · 2008
    18. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    19. The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine Expert Opinion on Biological Therapy · 2007
    20. Role of the Vitamin D Receptor in Hair Follicle Biology The Journal of Steroid Biochemistry and Molecular Biology · 2007
    21. Bone Morphogenetic Protein Signaling Regulates the Size of Hair Follicles and Modulates the Expression of Cell Cycle-Associated Genes Proceedings of the National Academy of Sciences of the United States of America · 2006
    22. Hair Cycle Control by Vanilloid Receptor-1 (TRPV1): Evidence from TRPV1 Knockout Mice Journal of Investigative Dermatology · 2006
    23. Wnt Signaling Induces Epithelial Differentiation During Cutaneous Wound Healing BMC Cell Biology · 2006
    24. Edar Signaling in the Control of Hair Follicle Development ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2005
    25. Sgk3 Links Growth Factor Signaling to Maintenance of Progenitor Cells in the Hair Follicle The Journal of Cell Biology · 2005
    26. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    27. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    28. Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis Molecular Endocrinology · 2004
    29. Canonical WNT Signaling Promotes Mammary Placode Development and Is Essential for Initiation of Mammary Gland Morphogenesis Development · 2004
    30. Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency Molecular and Cellular Biology · 2004
    31. Epithelial Growth Control by Neurotrophins: Leads and Lessons from the Hair Follicle Progress in brain research · 2004
    32. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003
    33. Stimulation of Ectodermal Organ Development by Ectodysplasin-A1 Developmental Biology · 2003
    34. Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin The FASEB Journal · 2003
    35. Cyclic Alopecia in Msx2 Mutants: Defects in Hair Cycling and Hair Shaft Differentiation Development · 2002
    36. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    37. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001
    38. P53 Involvement in the Control of Murine Hair Follicle Regression American Journal of Pathology · 2001
    39. Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2000
    40. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    41. Hair Follicle Biology, the Sebaceous Gland, and Scarring Alopecias Archives of dermatology · 1999
    42. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    43. The Use of Dermal Papilla Cells in Studies of Normal and Abnormal Hair Follicle Biology Dermatologic Clinics · 1996
    44. Induction of Follicle Formation and Hair Growth by Vibrissa Dermal Papillae Implanted into Rat Ear Wounds: Vibrissa-Type Fibres Are Specified Development · 1992
    45. The Secret Life of the Hair Follicle Trends in genetics · 1992

    Related research 4

    1. Reprogramming of Three-Dimensional Microenvironments for In Vitro Hair Follicle Induction bioRxiv (Cold Spring Harbor Laboratory) · 2022
    2. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    3. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011
    4. Mouse Notch: Expression in Hair Follicles Correlates with Cell Fate Determination ˜The œjournal of cell biology/˜The œJournal of cell biology · 1993