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    Glossary Noggin

    protein inhibiting BMPs, crucial for hair follicle development

    Noggin is a protein that plays a crucial role in the development and growth of various tissues, including hair follicles. It functions by inhibiting bone morphogenetic proteins (BMPs), which are involved in the regulation of cell growth and differentiation. By modulating BMP activity, Noggin helps maintain the balance necessary for proper hair follicle formation and cycling.

    Research 10 of 565

    1. Noggin is required for induction of the hair follicle growth phase in postnatal skin The FASEB Journal · 2001 · 211 citations
    2. Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop Genes & Development · 2012 · 138 citations
    3. Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation EMBO journal · 2003 · 65 citations
    4. The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects Developmental Dynamics · 2006 · 49 citations
    5. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways American Journal Of Pathology · 2009 · 45 citations
    6. Expression characteristics of BMP2, BMPR-IA and Noggin in different stages of hair follicle in yak skin General and comparative endocrinology · 2017 · 19 citations
    7. Effect of tofacitinib on the expression of noggin/BMP-4 and hair growth stimulation in mice Archives of Dermatological Research · 2018 · 2 citations
    8. The role of Wnt and Shh signaling systems in noggin-induced tumorigenesis Vestnik Rossijskogo universiteta družby narodov. Seriâ Agronomiâ i životnovodstvo · 2024
    9. Faculty Opinions recommendation of Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009
    10. Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin. Bradford Scholars (University of Bradford) · 2009
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