Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin

    October 2001 in “ The FASEB Journal ”
    Vladimir A. Botchkarev, Natalia V. Botchkareva, Motonobu Nakamura … Barbara A. Gilchrest
    Studysummary This study found that the BMP antagonist noggin induces hair growth in postnatal skin by neutralizing BMP4's inhibitory activity, potentially mediated by changes in Shh expression.
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    Research cited in this study 16

    1. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    2. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    3. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000
    4. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000
    5. Edar/Eda Interactions Regulate Enamel Knot Formation in Tooth Morphogenesis Development · 2000
    6. A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression The FASEB Journal · 2000
    7. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000
    8. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    9. Induction of the Hair Growth Phase in Postnatal Mice by Localized Transient Expression of Sonic Hedgehog Journal of Clinical Investigation · 1999
    10. Treatment of Hair Loss The New England Journal of Medicine · 1999
    11. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    12. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    13. Melanogenesis During the Anagen-Catagen-Telogen Transformation of the Murine Hair Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    14. Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles Differentiation · 1994
    15. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    16. Growth of the Hair Physiological Reviews · 1954

    Related research 3

    1. Bone Morphogenetic Protein Signaling Controls Hair Pigmentation Through Cross-Talk With the Melanocortin Receptor-1 Pathway Proceedings of the National Academy of Sciences · 2004
    2. Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling ˜The œAmerican journal of pathology · 2004
    3. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001