Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis

    February 2001 in “ Journal of Clinical Investigation ”
    Kimihiko Yano, Lawrence F. Brown, Michael Detmar
    Studysummary This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.
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    Research cited in this study 10

    1. The Role of VEGF and Thrombospondins in Skin Angiogenesis Journal of Dermatological Science · 2000
    2. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    3. Expression of Vascular Endothelial Growth Factor (VEGF) in Various Compartments of the Human Hair Follicle Archives of Dermatological Research · 1998
    4. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    5. Angiogenesis: A Dynamic Balance of Stimulators and Inhibitors Thrombosis and Haemostasis · 1997
    6. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996
    7. Loss of Vascular Endothelial Growth Factor in Human Alopecia Hair Follicles Journal of Investigative Dermatology · 1995
    8. The Secret Life of the Hair Follicle Trends in genetics · 1992
    9. Circulatory Changes in Alopecia Archives of Dermatology · 1961
    10. Growth of the Hair Physiological Reviews · 1954

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