Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells
January 1996
in “
Journal of Investigative Dermatology
”
Research cited in this study
4 / 4 results
research Loss of Vascular Endothelial Growth Factor in Human Alopecia Hair Follicles
Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
research Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development
FGF and EGF are crucial for hair follicle development and growth.
research Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
Related Research
2 / 2 resultsresearch Role of Vascular Endothelial Growth Factor in Hair Follicle Biology
Vascular endothelial growth factor (VEGF) was identified as a crucial regulator of angiogenesis and played a significant role in hair follicle growth and cycle modulation. As an autocrine growth factor in dermal papilla cells, VEGF stimulated hair follicle growth. In endothelial cells, VEGF functioned by binding to its receptor, leading to receptor dimerization, autophosphorylation, and activation of intracellular signaling pathways. However, it remained unclear whether this molecular mechanism was present in hair follicle growth.