The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine

    February 2007 in “ Expert Opinion on Biological Therapy ”
    Robert M. Hoffman
    Image of study
    TLDR Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
    The 2007 document highlights the discovery that hair follicle bulge area contains pluripotent adult stem cells expressing nestin and CD34, which can differentiate into various cell types such as neurons, glia, and smooth muscle cells. These stem cells have been successfully used in vivo to promote nerve regeneration and functional recovery in mice with severed sciatic or tibial nerves, by differentiating primarily into Schwann cells. The findings suggest that hair follicle stem cells could serve as a valuable source for autologous stem cell therapy for peripheral nerve injuries, offering a solution without the ethical concerns of embryonic stem cells. While the potential for hair restoration is mentioned, it is not the main focus of the document.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Please explain this Minoxidil phenomena

      in Minoxidil  58 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

    Related Research

    2 / 2 results