The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine

    February 2007 in “ Expert Opinion on Biological Therapy ”
    Robert M. Hoffman
    Studysummary This study found that hair follicle stem cells can effectively enhance nerve regeneration and restore function in peripheral nerve injuries in mice, suggesting their potential as a source for autologous stem cell therapy.
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    Research cited in this study 11

    1. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006
    2. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005
    3. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    4. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    5. Hair Follicle Dermal Cells Differentiate Into Adipogenic and Osteogenic Lineages Experimental Dermatology · 2003
    6. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    7. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003
    8. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    9. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    10. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    11. Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes Journal of Investigative Dermatology · 1999

    Related research 4

    1. Future Directions: The Known and Unknown Roles of Hair-Follicle Stem Cell Types 2010
    2. The Hair Follicle Stem Cell As The Paradigm Multipotent Adult Stem Cell Springer eBooks · 2008
    3. The Potential of Nestin-Expressing Hair Follicle Stem Cells in Regenerative Medicine Expert Opinion on Biological Therapy · 2007
    4. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005