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    Glossary Bulge Region

    specific area in hair follicle housing stem cells

    The bulge region is a specific area located in the outer root sheath of a hair follicle. It contains a reservoir of stem cells that are crucial for hair growth and regeneration. These stem cells can also contribute to the repair of the skin and other tissues, making the bulge region essential for both hair health and overall skin maintenance.

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    1. Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles Differentiation · 1994 · 130 citations
    2. Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata 2010 · 20 citations
    3. Human keratinocytes derived from the bulge region of hair follicles are refractory to differentiation International journal of oncology · 2009 · 8 citations
    4. In vitro identification of a stem cell population from canine hair follicle bulge region 2017 · 5 citations
    5. The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z‐protein in cells of the bulge region 1999 · 5 citations
    6. The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z-protein in cells of the bulge region 1999 · 2 citations
    7. Isolation, Cultivation, and Morphological Characteristics of Hair Follicle Adult Stem Cells in the Bulge Region in Mouse and Human Microscopy research · 2020 · 1 citations
    8. Immune response involving the bulge region in addition to telogen conversion contributes to hair loss in a case of atypical drug-induced hypersensitivity syndrome The Journal of Dermatology · 2013 · 1 citations
    9. Abstract 4300: Constitutive activation of Stat3 increases hair follicle progenitor population at the expense of bulge region keratinocyte stem cells Cancer Research · 2010
    10. Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle Archives of Dermatological Research · 1999 · 107 citations
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