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GlossaryTrichorrhexis Invaginata

hair shaft abnormality resembling bamboo segments, linked to Netherton Syndrome

Trichorrhexis Invaginata, also known as "bamboo hair," is a hair shaft abnormality where the hair appears to have nodes or bulges, resembling the segments of bamboo. This condition is often associated with Netherton Syndrome, a genetic disorder that also includes symptoms like ichthyosis (scaly skin) and a predisposition to allergies.

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research Netherton's Syndrome: A Syndrome of Elevated IgE and Characteristic Skin and Hair Findings

124 citations, January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.

research Dermatoscopy of Hair Shaft Disorders

68 citations, August 2012 in “Journal of the American Academy of Dermatology”

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

research Lanceolate Hair-J (LahJ): A Mouse Model for Human Hair Disorders

37 citations, June 2000 in “Experimental dermatology”

The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.

research Trichoscopy in Hair Shaft Disorders

36 citations, August 2018 in “Dermatologic Clinics”

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

research Prognosis and Management of Congenital Hair Shaft Disorders with Fragility—Part I

33 citations, June 2016 in “Pediatric Dermatology”

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

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community Does low HGH leading to hairloss?

in Research/Science 13 upvotes 9 months ago

The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.