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Glossary Hair Bulge

region in hair follicle housing stem cells for growth

The hair bulge is a region located in the outer root sheath of the hair follicle, near the base of the hair shaft. It serves as a reservoir for stem cells that are crucial for hair growth and regeneration, as well as for the repair of the skin after injury. This area plays a significant role in the hair growth cycle and is a key focus in research on hair loss and regenerative medicine.

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Research

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research Pilomatricoma can differentiate not only towards hair matrix and hair cortex, but also follicular infundibulum, outer root sheath and hair bulge

18 citations , March 2009 in “Experimental Dermatology”

This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.

research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region as Well as the Hair Bulb Area in the Chronic Alopecia Areata Patients

18 citations , January 2017 in “Annals of dermatology/Annals of Dermatology”

This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.

research Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis

5 citations , May 2020 in “Life science alliance”

This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.

research Milia may originate from the outermost layers of the hair bulge of the outer root sheath: A case report

November 2016 in “Oncology Letters”

This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.

research Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge

387 citations , November 2003 in “Journal of Investigative Dermatology”

The K15 promoter effectively targets stem cells in the hair follicle bulge.

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Community Join

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community Hair Transplant Recommendations Within $3000 Budget

in Basic Questions 78 upvotes 1 month ago

The user is seeking recommendations for countries to get a hair transplant with a budget of £3000. They are considering treatments like Minoxidil, finasteride, and RU58841.

community Budget LLLT Options: Are the under $200 products legit?

in Technology 8 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically the effectiveness and legitimacy of low-level laser therapy (LLLT) devices under $200. The user has seen positive results with finasteride, minoxidil, ketoconazole, microneedling, and scalp massages, and seeks advice on affordable LLLT options.

community Finally going to bite the bullet, pic for current UK

in Finasteride/Dutasteride 86 upvotes 1 year ago

The conversation discusses hair loss treatments, recommending starting with finasteride and minoxidil, possibly adding dutasteride later. Users suggest using a combination of oral and topical treatments, micro-needling, and nizoral shampoo, while emphasizing realistic expectations and the need for lifelong commitment to treatment.

community I’ve bit the bullet and ordered Dut.

in Finasteride/Dutasteride 7 upvotes 1 month ago

The conversation discusses switching from finasteride to dutasteride for hair loss treatment, with users sharing experiences and strategies for transitioning, such as alternating days or gradual introduction to avoid shedding. Some users report worsening hair conditions and side effects like low libido after switching.

community Seeking Reliable Online Pharmacy for Finasteride in Bulgaria

in Basic Questions 53 upvotes 1 month ago

A user in Bulgaria is seeking a reliable online pharmacy to purchase finasteride for hair loss treatment. They are stressed and willing to pay any price for a trustworthy source, even considering driving to a pharmacy that sells it without a prescription.

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Learn

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learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

What does the donor area look like after a hair transplant? The donor area may show slight redness and tiny scars but usually heals well and is often concealed by remaining hair.
How long does it take for the donor area to heal after a hair transplant? Surface healing of the donor area usually takes 1–2 weeks; redness, soreness and numbness can last longer.
Can women get hair transplants? Some women are candidates for a hair transplant, but diffuse thinning and a thin donor area limit who is suitable. Clinics say a careful assessment of the cause comes first.

learn Scalp Micropigmentation

Can scalp micropigmentation work for long hair? Providers say SMP can add the look of density under longer hair, but most say it works best with short hair, and results vary.

learn Hair Fibers

cosmetic product that temporarily makes hair appear thicker

Do hair fibers really make thinning hair look fuller, or is it just an illusion? Hair fibers create an optical illusion of fullness but do not actually thicken hair.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas