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    Did you mean Bone Morphogenetic Protein 4?
    Glossary Bone Morphogenetic Protein 4

    regulates hair follicle growth and tissue development

    Bone Morphogenetic Protein 4 (BMP4) is a protein that plays a crucial role in the development and growth of various tissues, including bone and hair follicles. It is part of the transforming growth factor-beta (TGF-β) superfamily and is involved in cellular processes such as differentiation, proliferation, and apoptosis. In the context of hair, BMP4 helps regulate the growth cycle of hair follicles and can influence conditions like alopecia.

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    1. Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Proceedings of the National Academy of Sciences · 2004 · 70 citations
    2. Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin. Bradford Scholars (University of Bradford) · 2009
    3. Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Research · 2002 · 79 citations
    4. Implications of constitutively active bone morphogenetic protein (BMP) signaling in skin morphogenesis and skin postnatal homeostasis University of Southern California Digital Library · 2011
    5. Anti-wrinkle effect of bone morphogenetic protein receptor 1a-extracellular domain (BMPR1a-ECD) BMB Reports · 2013 · 5 citations
    6. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways American Journal Of Pathology · 2009 · 45 citations
    7. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006 · 176 citations
    8. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes Proceedings of the National Academy of Sciences of the United States of America · 2006 · 92 citations
    9. Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling ˜The œAmerican journal of pathology · 2004 · 65 citations
    10. Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface ˜The œAmerican journal of pathology · 2008 · 41 citations
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    1. Follistatin Protein that blocks activin, a growth-regulating signal
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