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This study found that an improved flap model in nude mice significantly reduces the time needed for hair induction compared to the traditional method, likely due to enhanced blood supply at the transplantation sites.

This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.

This study demonstrates that encapsulating cell-free fat extract in a gelatin methacrylate hydrogel enhances flap repair by sustaining angiogenesis, reducing oxidative stress, and offering favorable biocompatibility in a murine skin flap model, thereby advancing potential clinical flap necrosis treatments.

This study found that the hydrophilic PTK-UR foam with EG7 repeats significantly improved wound healing in porcine skin wounds compared to other scaffolds, suggesting potential for synthetic biomaterial applications.

In a study using mouse models, researchers developed a gelatin methacryloyl scaffold with calcium-doped silica nanoparticles loaded with deferoxamine, which significantly improved skin flap survival and hair follicle growth, suggesting potential clinical applications in tissue regeneration.