8 citations,
January 2015 in “Clinical and Experimental Dermatology” A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.
4 citations,
June 2013 in “Aesthetic Plastic Surgery” Minoxidil improved rat skin flap survival but was less effective than surgical methods.
1 citations,
January 2019 in “Advances in Medical Sciences” The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.
14 citations,
November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
November 2008 in “Medical & surgical dermatology” A device was made in 2008 to measure hair loss severity. Other findings include: frizzy mutation in mice isn't related to Fgfr2, C/EBPx marks preadipocytes, Cyclosporin A speeds up hair growth in mice, blocking plasmin and metalloproteinases hinders healing, hyperbaric oxygen helps ischemic wound healing, amniotic membranes heal wounds better than polyurethane foam, rhVEGF165 from a fibrin matrix improves tissue flap viability and induces VEGF-R2 expression, and bFGF enhances wound healing and reduces scarring in rabbits.
26 citations,
July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
6 citations,
September 2012 in “Aesthetic Plastic Surgery” Minoxidil applied before and after surgery improves skin flap survival in rats.
12 citations,
August 2015 in “Plastic Surgery” Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
6 citations,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
April 2016 in “Plastic and reconstructive surgery. Global open” The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.
36 citations,
August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
80 citations,
April 2017 in “Frontiers in Pharmacology” PDRN helps repair tissue and improve wound healing with a high safety profile.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
August 2004 in “Journal of the American College of Surgeons” Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.
63 citations,
September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
7 citations,
December 2012 in “PubMed” Azelaic acid and finasteride can help preserve skin flaps after surgery by increasing BCL-2 protein and decreasing bax protein.
15 citations,
May 2015 in “Photomedicine and Laser Surgery” Low-Level Laser Therapy may help with flap survival and burn scar healing, but not with venous ulcers or hair loss, and more research is needed.
16 citations,
March 2018 in “Plastic and Reconstructive Surgery – Global Open” Early surgical treatment for severe facial injuries from high-energy impacts leads to better recovery.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
22 citations,
December 1998 in “Dermatologic Surgery” A new storage solution may increase hair transplant graft survival.
21 citations,
November 2020 in “Chemical Engineering Journal” The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.
16 citations,
December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
September 2024 in “Journal of Cutaneous and Aesthetic Surgery” A young man with severe neck and beard burns was successfully treated, restoring neck movement and improving skin appearance.
7 citations,
March 2017 in “Annals of Plastic Surgery” The new Mercedes flap variant effectively closed medium-sized scalp defects in a single operation with good cosmetic results and no complications.
September 2006 in “Plastic and Reconstructive Surgery” The SGAP flap effectively treats large sacral pressure sores with good results and minimal complications.