The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics

February 2021 in “ Pharmacological research ”

Mingchen Xiong, Qi Zhang, Weijie Hu, Chongru Zhao, Wenchang Lv, Yi Yi, Yichen Wang, Huiping Tang, Min Wu, Yiping Wu

exosomes nanoscale vesicles biomolecules skin health cell communication skin development endogenic exosomes exogenous exosomes stem cells skin repair skin regeneration skin rejuvenation skin microenvironment dermatology cutaneous medical aesthetics

Studysummary This review discusses the potential of endogenic and exogenous exosomes in dermatology and cutaneous aesthetics, highlighting their capacity to repair and rejuvenate skin tissue, but reports no new experimental results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Exosomes, nanoscale vesicles derived from cells, played a significant role in skin health by carrying biomolecules that facilitate communication between cells. They were crucial in both physiological and pathological skin development. Endogenic exosomes influenced skin stability and function, while exogenous exosomes, such as those from stem cells, offered promising new treatments for skin repair, regeneration, and rejuvenation. Understanding the mechanisms of exosomes in the skin microenvironment had the potential to lead to innovative therapeutic methods in dermatology and cutaneous medical aesthetics.

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