A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

    April 2019 in “ ACS nano ”
    Guang Yang, Qian Chen, Di Wen, Zhaowei Chen, Jinqiang Wang, Guojun Chen, Zejun Wang, Xudong Zhang, Yuqi Zhang, Quanyin Hu, Liang Zhang, Zhen Gu
    From the encyclopedia
    Exosomes →

    Microscopic delivery system that sends growth-promoting signals to hair follicles

    Keratin →
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    Studysummary In a mouse model, this study demonstrated that a microneedle patch system using keratin and integrated with MSC-derived exosomes and UK5099 promoted hair regrowth more efficiently than traditional delivery methods.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study developed a microneedle patch made from hair-derived keratin to promote hair regrowth by delivering exosomes and the drug UK5099 directly to hair follicles. In a mouse model, this method showed superior efficacy, faster hair cycle activation, and higher hair density and thickness compared to conventional treatments. The microneedle system was biocompatible, minimally invasive, and provided visible results within 6 days, offering a promising strategy for hair loss therapy.
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