The Roles of Exosomes in Regulating Hair Follicle Growth

    Ming Cheng, Cong Ma, Hong‐Duo Chen, Yan Wu, Xue‐Gang Xu
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    TLDR Exosomes can help promote hair growth and may treat hair loss.
    Recent research highlights the potential of exosomes in promoting hair follicle growth, offering a novel treatment avenue for alopecia. Exosomes can enhance hair growth by modulating cellular pathways and promoting the proliferation of hair follicle cells. Exosomes derived from dermal papilla cells and mesenchymal stem cells have shown promising results in both in vitro and in vivo studies. A retrospective study in South Korea involving 39 patients with alopecia demonstrated significant improvements in hair density and thickness after 12 weeks of treatment with adipose-derived stem cell exosomes. Despite these promising findings, the clinical application of exosome therapy for hair growth is still in its early stages, with many uncertainties regarding mechanisms, safety, and optimal treatment protocols.
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