TLDR A woman regrew her hair after receiving injections of special cell-derived vesicles.
This case report details the successful treatment of a 36-year-old woman with persistent chemotherapy-induced alopecia (PCIA) using extracellular vesicles (EVs) derived from human placental mesenchymal stromal cells (MSCs). The patient, who had undergone chemotherapy for invasive ductal carcinoma, experienced no significant hair regrowth for 18 months post-treatment. She received subcutaneous injections of MSC-derived EVs every 4 weeks for 3 months, resulting in complete regrowth of terminal hair on her scalp. The study suggests that MSC-derived EVs could be a potential treatment for PCIA, though further research with a larger patient cohort is necessary to confirm these findings.
13 citations,
December 2021 in “Journal of Cellular and Molecular Medicine” Exosome-enriched vesicles from placental cells improved skin condition in a patient with chronic graft-versus-host disease.
113 citations,
November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
57 citations,
March 2011 in “The American Journal of Dermatopathology” Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.
48 citations,
August 2010 in “PubMed” Chemotherapy often causes hair loss, which is distressing for many, but usually reversible.
December 2024 in “International Journal of Molecular Sciences” Human umbilical cord stem cell vesicles may help treat aging and related diseases.
1 citations,
September 2023 in “Stem cell research & therapy” Mesenchymal stem cells could help treat aging-related diseases better than current methods.
15 citations,
May 2021 in “British journal of dermatology/British journal of dermatology, Supplement” Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
2 citations,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
