Chemotherapy-Induced Hair Loss

Chemotherapy-induced hair loss had an estimated incidence of 65%, with 47% of female patients considering it the most traumatic aspect of treatment and 8% potentially declining chemotherapy due to fear of hair loss. No approved pharmacologic interventions existed to prevent this side effect, though topical minoxidil was found to reduce severity or duration but not prevent hair loss. Scalp cooling was the primary method to minimize hair loss, but the quality of data supporting its effectiveness was poor. The condition was usually reversible, though some patients experienced changes in hair color, texture, or density. Temporary use of wigs and proper hair and scalp care were recommended coping strategies.