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GlossaryExtracellular Vesicles (EVs)

tiny, membrane-bound particles released by cells for communication

Extracellular Vesicles (EVs) are tiny, membrane-bound particles released by cells into the surrounding environment. They play a crucial role in cell-to-cell communication by transporting proteins, lipids, and genetic material between cells, which can influence various biological processes, including immune responses and tissue repair.

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research Adipose Tissue Protects Against Skin Photodamage Through CD151- And AdipoQ- EVs

December 2024 in “Cell Communication and Signaling”

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

research Baricitinib-Loaded EVs Promote Alopecia Areata Mouse Hair Regrowth by Reducing JAK-STAT-Mediated Inflammation and Promoting Hair Follicle Regeneration

December 2024 in “Drug Discoveries & Therapeutics”

Baricitinib-loaded EVs help hair regrowth in alopecia areata by reducing inflammation and promoting hair follicle regeneration.

research The Therapeutic Role of ADSC-EVs in Skin Regeneration

7 citations, June 2022 in “Frontiers in Medicine”

ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.

research Exosomes/EVs: Advanced Cell-Based Therapies for Hair Loss: A Comprehensive Systematic Review

May 2023 in “Cytotherapy”

research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

271 citations, May 2019 in “Cells”

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

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community Horrible news, Stemson Therapeutics has shut down

in Technology 193 upvotes 1 month ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Why I deleted my YouTube channel Part I

in Update 118 upvotes 3 years ago

A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community The Cure isn't 5 years away; it's already here.

in Research/Science 995 upvotes 3 weeks ago

PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.