Human Placental Mesenchymal Stromal Cell-Derived Exosome-Enriched Extracellular Vesicles for Chronic Cutaneous Graft-Versus-Host Disease: A Case Report

December 2021 in “ Journal of Cellular and Molecular Medicine ”

Amir Hossein Norooznezhad, Reza Yarani, Mehrdad Payandeh, Zohreh Hoseinkhani, Sarah Kiani, Elham Taghizadeh, Avnesh S. Thakor, Kamran Mansouri

exosome-enriched extracellular vesicles human placental mesenchymal stromal cells chronic cutaneous graft-versus-host disease hyperpigmentation ulcers skin condition monocyte levels EVs hPMSCs cGVHD

Studysummary This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.

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research Human Placental Mesenchymal Stromal Cell-Derived Exosome-Enriched Extracellular Vesicles for Chronic Cutaneous Graft-Versus-Host Disease: A Case Report

13 citations , December 2021 in “Journal of Cellular and Molecular Medicine”

This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.