Exosomes for Repair, Regeneration, and Rejuvenation

    Joydeep Basu, John W. Ludlow
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    TLDR Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
    The document from 2016 explores the potential of exosomes in regenerative medicine, highlighting their role in cell communication and their ability to mimic the regenerative effects of stem cells. Exosomes are small vesicles that can transfer proteins and nucleic acids between cells, and they have been shown to improve disease biomarkers and promote tissue regeneration in various animal models. They offer several advantages over cell-based therapies, including stability, lower risk of immune rejection, and ease of production. While exosomes have been used in clinical settings, such as treating graft-versus-host disease, and show promise in skin repair and hair growth, challenges remain in large-scale manufacturing and regulatory control. The document suggests that exosomes could potentially replace live cell therapies in certain applications, but further research is needed to identify the specific components that mediate regenerative outcomes and to establish manufacturing and quality control processes.
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      community Has anyone tried Exosomes from Musely or somewhere else?

      in Hair Systems  3 upvotes 2 weeks ago
      Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community How Does Exosome Therapy Work for Hair Loss?

      in Research/Science  5 upvotes 1 year ago
      Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

      community How is no one talking about this?

      in Treatment  6 upvotes 3 months ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

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