TLDR Liposomes could improve how skin care products work but are costly and not very stable.
The document from 2012 discusses the use of liposomes in cosmeceuticals, emphasizing their potential in enhancing the delivery and efficacy of active ingredients for skin care and treatment. Liposomes are microscopic vesicles that can encapsulate both hydrophilic and lipophilic drugs, improving their delivery to the skin and reducing systemic absorption. They are suitable for topical delivery due to their biocompatibility, biodegradability, and ability to merge with cell membranes. The document highlights their advantages, such as increased drug accumulation at the skin, reduced side effects, and sustained release of active compounds, but also acknowledges disadvantages like low stability and high manufacturing costs. Studies mentioned include a 23-patient study on melasma treatment with liposomal 4-n-butylresorcinol 0.1% cream, and liposomal formulations of minoxidil and finasteride for alopecia, which may enhance drug delivery to hair follicles with reduced systemic side effects. Liposomes have also been used for UV protection, as carriers for antioxidants, and in treatments for various skin conditions such as hyperpigmentation, vitiligo, and wound healing. Despite their potential, commercialization is limited by costs and stability issues, and the document calls for more research in developing new cosmeceutical formulations.
Cited in this study
12 / 12 results
11 citations
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April 2011 in “Biomolecules & Therapeutics”
24 citations
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November 2010 in “Pharmaceutical Development and Technology” Transcutol P best increases Finasteride absorption for hair loss treatment.
140 citations
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April 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
85 citations
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February 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
127 citations
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October 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
141 citations
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December 2005 in “International journal of pharmaceutics” Hair follicles may soon be used more for targeted and systemic drug delivery.
205 citations
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January 2005 in “Skin pharmacology and physiology” Liposomes and niosomes can help drugs penetrate the skin better.
34 citations
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March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
55 citations
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January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
32 citations
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November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
111 citations
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March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.