TLDR Liposomes improve drug delivery and reduce skin irritation in dermatology.
Liposomes, consisting of spherical phospholipid bi-layers, have been extensively researched over the past 30 years and are now tailored for various dermatological applications. They serve as carriers for both hydrophilic and lipophilic therapeutic agents, enhancing drug stability and penetration through the skin. Liposomes reduce skin irritation by sustaining drug release and hydrating the epidermis, and they can target drugs to hair follicles, benefiting hair follicle-associated disorders. Clinical data showed that 5-ALA encapsulated in liposomes improved Fluorescence Diagnosis and optimized Photodynamic Therapy outcomes.
62 citations,
May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
4 citations,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
151 citations,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
111 citations,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
January 2024 in “Regenerative Biomaterials” Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.
