TLDR Liposomes improve drug delivery and reduce skin irritation in dermatology.
Liposomes, consisting of spherical phospholipid bi-layers, have been extensively researched over the past 30 years and are now tailored for various dermatological applications. They serve as carriers for both hydrophilic and lipophilic therapeutic agents, enhancing drug stability and penetration through the skin. Liposomes reduce skin irritation by sustaining drug release and hydrating the epidermis, and they can target drugs to hair follicles, benefiting hair follicle-associated disorders. Clinical data showed that 5-ALA encapsulated in liposomes improved Fluorescence Diagnosis and optimized Photodynamic Therapy outcomes.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
