TLDR Liposomes improve drug delivery and reduce skin irritation in dermatology.
Liposomes, consisting of spherical phospholipid bi-layers, have been extensively researched over the past 30 years and are now tailored for various dermatological applications. They serve as carriers for both hydrophilic and lipophilic therapeutic agents, enhancing drug stability and penetration through the skin. Liposomes reduce skin irritation by sustaining drug release and hydrating the epidermis, and they can target drugs to hair follicles, benefiting hair follicle-associated disorders. Clinical data showed that 5-ALA encapsulated in liposomes improved Fluorescence Diagnosis and optimized Photodynamic Therapy outcomes.
62 citations
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May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
4 citations
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February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
73 citations
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February 2023 in “Polymers” Peptide hydrogels are promising for drug delivery and tissue repair in medicine.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
151 citations
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July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
