Transfollicular Drug Delivery: Is It a Reality?

    Victor M. Meidan, Michael Bonner, B. B. Michniak
    Studysummary This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin Journal of Investigative Dermatology · 2005
    2. RU 58841-Myristate Prodrug Development for Topical Treatment of Acne and Androgenetic Alopecia PubMed · 2005
    3. Time and Depth Resolved Visualization of the Diffusion of a Lipophilic Dye into the Hair Follicle of Fresh Unfixed Human Scalp Skin Journal of Controlled Release · 2004
    4. Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles Journal of controlled release · 2004
    5. Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    6. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    7. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004
    8. Permeant Lipophilicity and Vehicle Composition Influence Accumulation of Dyes in Hair Follicles of Human Skin European journal of pharmaceutical sciences · 2003
    9. Electroosmotic Pore Transport in Human Skin Pharmaceutical Research · 2003
    10. Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle Journal of controlled release · 2002
    11. The Arrector Pili Muscle and the Follicular Unit of the Scalp: A Microscopic Anatomy Study Dermatologic Surgery · 2002
    12. Follicular Liposomal Delivery Systems Journal of liposome research · 2002
    13. Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro Journal of drug targeting · 2002
    14. On the Use of Micro-Imager to Directly Visualize Drug Distribution in Human Skin Skin pharmacology and physiology · 2001
    15. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001
    16. Efficient Delivery of Transgenes to Human Hair Follicle Progenitor Cells Using Topical Lipoplex Nature biotechnology · 2000
    17. Description of the Intrafollicular Delivery of Large Molecular Weight Molecules to Follicles of Human Scalp Skin In Vitro Journal of Pharmaceutical Sciences · 1997
    18. Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes Journal of Pharmaceutical Sciences · 1997
    19. Topical Liposome Delivery of Molecules to Hair Follicles in Mice Journal of Dermatological Science · 1997
    20. The Use of Autoradiography to Study the Localization of Germicides in Skin British Journal of Dermatology · 1969