Transfollicular Drug Delivery: Is It a Reality?

    Victor M. Meidan, Michael Bonner, B. B. Michniak
    Image of study
    TLDR Hair follicles may soon be used more for targeted and systemic drug delivery.
    In the document from December 2005, hair follicles and sebaceous glands were increasingly recognized as important for percutaneous drug delivery. The pilosebaceous units were being considered for localized treatments, especially for conditions like acne and alopecia, and also for systemic drug delivery. The paper reviewed the anatomy and physiology of these units, the design and effectiveness of formulations targeting the follicles, and the development of quantitative models. It highlighted that novel developments were expected to significantly enhance the understanding of transfollicular drug delivery in the near future.
    Discuss this study in the Community →

    Research cited in this study

    20 / 20 results

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Verteporfin day 119 update - donor hair regeneration human trial

      in Research/Science  146 upvotes 3 years ago
      A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

      community Switched from finasteride to dutasteride - 2 month update

      in Finasteride/Dutasteride  6 upvotes 2 years ago
      The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

      community Fin/Min/VitD 3 month progress pics

       113 upvotes 7 years ago
      A user shared their positive 3-month experience using finasteride, minoxidil, and vitamin D to treat hair loss, noting significant regrowth and minimal shedding. They also discussed potential side effects and the low likelihood of experiencing them, while being open to answering further questions.

    Similar Research

    6 / 1000+ results