Treatments for Androgenetic Alopecia and Alopecia Areata

    January 2001 in “ Drugs ”
    Victor M. Meidan, Elka Touitou
    Studysummary This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 38

    1. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    2. The Penetration Enhancer SEPA Augments Stimulation of Scalp Hair Growth by Topical Minoxidil in the Balding Stumptail Macaque Skin Pharmacology and Physiology · 2009
    3. Efficient Delivery of Transgenes to Human Hair Follicle Progenitor Cells Using Topical Lipoplex Nature biotechnology · 2000
    4. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    5. Hair Regrowth Dermatologic Clinics · 1998
    6. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    7. Fibre Optic Confocal Imaging of Keratinocytes, Blood Vessels, and Nerves in Hairless Mouse Skin In Vivo Journal of Anatomy · 1998
    8. Alopecia Universalis Associated With a Mutation in the Human Hairless Gene Science · 1998
    9. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    10. Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia Dermatology · 1998
    11. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    12. 5α-Reductase Inhibitors: A New Hope in Dermatology? International Journal of Dermatology · 1997
    13. Topical Liposome Delivery of Molecules to Hair Follicles in Mice Journal of Dermatological Science · 1997
    14. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997
    15. Whole Hair Follicle Culture Dermatologic clinics · 1996
    16. Treatment of Alopecia Areata Dermatologic clinics · 1996
    17. Effects of Hypertrichotic Agents on Follicular and Nonfollicular Cells In Vitro Skin Pharmacology and Physiology · 1996
    18. PUVA Treatment of Alopecia Areata Partialis, Totalis, and Universalis: Audit of 10 Years' Experience at St John's Institute of Dermatology British journal of dermatology/British journal of dermatology, Supplement · 1995
    19. Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride Archives of Dermatology · 1995
    20. The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques The Journal of Clinical Endocrinology and Metabolism · 1994
    21. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994
    22. Androgenetic Alopecia in the Female Archives of Dermatology · 1994
    23. Chemical Agents and Peptides Affect Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    24. Minoxidil: Update on Its Clinical Role PubMed · 1993
    25. Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque The Journal of Clinical Endocrinology and Metabolism · 1992
    26. Quantitative Models for the Study of Hair Growth In Vivo Annals of the New York Academy of Sciences · 1991
    27. Treatment-Resistant Alopecia Areata: Response to Combination Therapy with Minoxidil Plus Anthralin Archives of Dermatology · 1990
    28. Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution Journal of Pharmaceutical Sciences · 1990
    29. Five-Year Follow-Up of Men with Androgenetic Alopecia Treated with Topical Minoxidil Journal of The American Academy of Dermatology · 1990
    30. Evaluation of Anthralin in the Treatment of Alopecia Areata Archives of dermatology · 1987
    31. Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia Journal of The American Academy of Dermatology · 1987
    32. Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata Journal of The American Academy of Dermatology · 1987
    33. Long-Term Follow-Up of Men with Male Pattern Baldness Treated with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    34. Dose-Response Study of Topical Minoxidil in Male Pattern Alopecia Journal of The American Academy of Dermatology · 1987
    35. Topical Tretinoin for Hair Growth Promotion Journal of the American Academy of Dermatology · 1986
    36. Topical Minoxidil in Early Male Pattern Baldness Journal of The American Academy of Dermatology · 1985
    37. Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia Archives of Dermatology · 1985
    38. Testosterone Metabolism in the Skin: A Review of Its Function in Androgenetic Alopecia, Acne Vulgaris, and Idiopathic Hirsutism Including Recent Studies with Antiandrogens Archives of Dermatology · 1975

    Related research 8

    1. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    2. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    3. Pharmacological Therapeutics in Androgenetic Alopecia Journal of The Korean Medical Association · 2020
    4. Hair Disorders Oxford University Press eBooks · 2018
    5. Disorders of Hair DeckerMed Medicine · 2013
    6. Alopecia Areata: Clinical Presentation, Diagnosis, and Unusual Cases Dermatologic Therapy · 2011
    7. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    8. Treatments for Androgenetic Alopecia and Alopecia Areata Drugs · 2001