Hair Regrowth

April 1998 in “ Dermatologic Clinics ”

Jerry Shapiro, Vera H. Price

androgenetic alopecia alopecia areata finasteride antiandrogens minoxidil intralesional corticosteroids systemic corticosteroids topical immunotherapy DPCP targeted immunomodulatory agents gene therapy phototherapy AGA Propecia Rogaine corticosteroids diphenylcyclopropenone

TLDR Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The document from 1998 reviews various treatments for hair regrowth, focusing on androgenetic alopecia (AGA) and alopecia areata. It discusses the efficacy of finasteride in clinical trials with 1,879 men, showing significant hair count increases and improvements in assessments. The use of antiandrogens in women with AGA is noted, though less effective than for other conditions. Minoxidil is highlighted for its hair growth promotion, with studies involving 2,294 men and 256 women showing moderate to dense regrowth in a significant percentage of participants. The document also covers treatments for alopecia areata, including intralesional corticosteroids, systemic corticosteroids, and topical immunotherapy with agents like DPCP, with varying success rates. It emphasizes the need for continuous treatment and the psychological impact of severe alopecia areata. Future treatments such as targeted immunomodulatory agents, gene therapy, and new phototherapy techniques are also mentioned.

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research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

416 citations , September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

research Whole Hair Follicle Culture

57 citations , October 1996 in “Dermatologic clinics”

HA-MNs with MXD effectively treat hair loss better than topical MXD with fewer side effects.

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations , October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

research The Use of Dermal Papilla Cells in Studies of Normal and Abnormal Hair Follicle Biology

19 citations , October 1996 in “Dermatologic Clinics”

Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.

research Antiandrogen And Hormonal Treatment Of Acne

38 citations , October 1996 in “Dermatologic Clinics”

Certain hormone treatments can improve acne and related conditions in women.

research Guidelines of Care for Androgenetic Alopecia

37 citations , September 1996 in “Journal of The American Academy of Dermatology”

Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.

research PUVA Treatment of Alopecia Areata Partialis, Totalis, and Universalis: Audit of 10 Years' Experience at St John's Institute of Dermatology

105 citations , December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

PUVA treatment is generally ineffective for alopecia areata.

research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness

61 citations , September 1994 in “The Journal of Clinical Endocrinology and Metabolism”

research Androgenetic Alopecia in the Female

82 citations , March 1994 in “Archives of Dermatology”

2% topical minoxidil effectively treats female hair loss with minimal side effects.

research Minoxidil

24 citations , January 1993 in “Dermatologic Clinics”

Minoxidil effectively treats hair loss, works better for women, and requires consistent use.

research Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata

101 citations , November 1992 in “Archives of Dermatology”

Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations , October 1992 in “The New England Journal of Medicine”

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

research Topical Minoxidil in Alopecia Areata: No Effect on the Perifollicular Lymphoid Infiltration

33 citations , July 1992 in “Journal of Investigative Dermatology”

Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.

research Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp

124 citations , April 1992 in “Journal of Endocrinology/Journal of endocrinology”

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

40 citations , February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Taking finasteride pills and using minoxidil lotion together can help grow hair.

research The Clinical Development of a 5α-Reductase Inhibitor, Finasteride

211 citations , November 1990 in “The Journal of Steroid Biochemistry and Molecular Biology”

Finasteride effectively treats BPH, but needs more trials to understand potential.

research Five-Year Follow-Up of Men with Androgenetic Alopecia Treated with Topical Minoxidil

70 citations , April 1990 in “Journal of The American Academy of Dermatology”

Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.

research The Management of Androgenetic Alopecia in Women

8 citations , January 1989 in “Journal of Dermatological Treatment”

This text talks about how to treat hair loss in women. It suggests different options and stresses the importance of support.

research Clinical Applications of Antiandrogens

29 citations , October 1988 in “Journal of Steroid Biochemistry”

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

research Evaluation of Anthralin in the Treatment of Alopecia Areata

109 citations , November 1987 in “Archives of dermatology”

Anthralin cream helped 25% of patients with severe alopecia areata regrow hair, but caused skin irritation.

research Topical minoxidil in male pattern baldness: Effects of discontinuation of treatment

57 citations , July 1987 in “Journal of The American Academy of Dermatology”

Stopping minoxidil treatment resumes balding; continuous use needed for results.

research Use of topical minoxidil as a possible adjunct to hair transplant surgery

28 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil may help hair growth after transplant surgery.

research Topical minoxidil (3%) in extensive alopecia areata, including long-term efficacy

54 citations , March 1987 in “Journal of The American Academy of Dermatology”

3% topical minoxidil effectively treats extensive alopecia areata with few side effects.

research Long-term follow-up of men with male pattern baldness treated with topical minoxidil

51 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.

research Action of topical minoxidil in the bald stump-tailed macaque

78 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth but stops working when discontinued.

research Double-blind, placebo-controlled evaluation of topical minoxidil in extensive alopecia areata

104 citations , March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.

research Topical Minoxidil in Extensive Alopecia areata, Including 3-Year Follow-Up

34 citations , January 1987 in “Dermatology”

Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.

research Topical tretinoin for hair growth promotion

73 citations , October 1986 in “Journal of the American Academy of Dermatology”

Tretinoin may help hair growth and works better when combined with minoxidil.

research Dose-response study of topical minoxidil in male pattern baldness

58 citations , July 1986 in “Journal of The American Academy of Dermatology”

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

research Topical Minoxidil Dose-Response Effect in Alopecia Areata

54 citations , February 1986 in “Archives of Dermatology”

Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.

research Cyclic dynamics of hair follicles and the effect of minoxidil on the bald scalps of stumptailed macaques

54 citations , June 1985 in “American Journal of Dermatopathology”

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

research The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women

142 citations , February 1985 in “Fertility and sterility”

Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

research Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia

101 citations , January 1985 in “British Journal of Dermatology”

Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.

research Effective medical treatment for common baldness in women

43 citations , July 1984 in “Clinical and Experimental Dermatology”

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

research Effect of Minoxidil on Cultured Keratinocytes

72 citations , December 1983 in “Journal of Investigative Dermatology”

Minoxidil helps hair cells live longer and grow longer.

research Treatment of Hirsutism, Acne and Alopecia with Cyproterone Acetate

39 citations , January 1980 in “Dermatology”

Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.

research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex

666 citations , September 1977 in “British Journal of Dermatology”

Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.

research Pharmacology and Potential Use of Cyproterone Acetate

129 citations , January 1977 in “Hormone and metabolic research”

Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.

research Testosterone Metabolism in the Skin

74 citations , November 1975 in “Archives of dermatology”

Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.

research Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism

232 citations , June 1975 in “Journal of Steroid Biochemistry”

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

research Treatment of Alopecia Areata With Steroid Solution

30 citations , December 1972 in “Archives of dermatology”

The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.

research Alopecia Totalis

22 citations , March 1963 in “Archives of dermatology”

A woman regrew her hair significantly using a corticosteroid cream with a plastic cover.

5 / 5 results

research Disorders of Hair

July 2013 in “DeckerMed Family Medicine”

The document's conclusion cannot be provided because the document is not readable or understandable.

research Topical and Intralesional Therapies for Alopecia Areata

36 citations , May 2011 in “Dermatologic therapy”

No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.

research Interventions for Alopecia Areata

2 citations , February 2009 in “Journal of Evidence-Based Medicine”

No treatment showed significant long-term hair growth benefits for alopecia areata.

research Hair Regrowth

118 citations , April 1998 in “Dermatologic Clinics”

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

research Circulatory Changes in Alopecia

36 citations , November 1961 in “Archives of Dermatology”

The document suggests that the traditional understanding of hair growth cycles and alopecia may be inaccurate and that blood supply plays a significant role in hair growth and loss.