Hair Regrowth

April 1998 in “ Dermatologic Clinics ”

Jerry Shapiro, Vera H. Price

androgenetic alopecia alopecia areata finasteride antiandrogens minoxidil intralesional corticosteroids systemic corticosteroids topical immunotherapy DPCP targeted immunomodulatory agents gene therapy phototherapy AGA Propecia Rogaine corticosteroids diphenylcyclopropenone

TLDR Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The document from 1998 reviews various treatments for hair regrowth, focusing on androgenetic alopecia (AGA) and alopecia areata. It discusses the efficacy of finasteride in clinical trials with 1,879 men, showing significant hair count increases and improvements in assessments. The use of antiandrogens in women with AGA is noted, though less effective than for other conditions. Minoxidil is highlighted for its hair growth promotion, with studies involving 2,294 men and 256 women showing moderate to dense regrowth in a significant percentage of participants. The document also covers treatments for alopecia areata, including intralesional corticosteroids, systemic corticosteroids, and topical immunotherapy with agents like DPCP, with varying success rates. It emphasizes the need for continuous treatment and the psychological impact of severe alopecia areata. Future treatments such as targeted immunomodulatory agents, gene therapy, and new phototherapy techniques are also mentioned.

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Research cited in this study

44 / 44 results

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

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416 citations, September 1997 in “Journal of Investigative Dermatology”

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

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HA-MNs with MXD effectively treat hair loss better than topical MXD with fewer side effects.

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143 citations, October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

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Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.

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Certain hormone treatments can improve acne and related conditions in women.

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37 citations, September 1996 in “Journal of The American Academy of Dermatology”

Treat genetic hair loss early with FDA-approved medications and consider hair transplantation.

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105 citations, December 1995 in “British journal of dermatology/British journal of dermatology, Supplement”

PUVA treatment is generally ineffective for alopecia areata.

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61 citations, September 1994 in “The Journal of Clinical Endocrinology and Metabolism”

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82 citations, March 1994 in “Archives of Dermatology”

2% topical minoxidil effectively treats female hair loss with minimal side effects.

research Minoxidil

24 citations, January 1993 in “Dermatologic Clinics”

Minoxidil effectively treats hair loss, works better for women, and requires consistent use.

research Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata

101 citations, November 1992 in “Archives of Dermatology”

Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations, October 1992 in “The New England Journal of Medicine”

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

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33 citations, July 1992 in “Journal of Investigative Dermatology”

Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.

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124 citations, April 1992 in “Journal of Endocrinology/Journal of endocrinology”

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

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40 citations, February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Taking finasteride pills and using minoxidil lotion together can help grow hair.

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Most children treated with diphencyprone regrew some or all of their hair.

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Finasteride effectively treats BPH, but needs more trials to understand potential.

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Minoxidil treatment increased hair growth for up to 5 years, requiring twice daily application.

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This text talks about how to treat hair loss in women. It suggests different options and stresses the importance of support.

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29 citations, October 1988 in “Journal of Steroid Biochemistry”

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

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Anthralin cream helped 25% of patients with severe alopecia areata regrow hair, but caused skin irritation.

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Squaric acid dibutylester led to complete hair regrowth in 28.5% of patients with alopecia areata.

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57 citations, July 1987 in “Journal of The American Academy of Dermatology”

Stopping minoxidil treatment resumes balding; continuous use needed for results.

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28 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil may help hair growth after transplant surgery.

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54 citations, March 1987 in “Journal of The American Academy of Dermatology”

3% topical minoxidil effectively treats extensive alopecia areata with few side effects.

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51 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.

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78 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth but stops working when discontinued.

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104 citations, March 1987 in “Journal of The American Academy of Dermatology”

Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.

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Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.

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Tretinoin may help hair growth and works better when combined with minoxidil.

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Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

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Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.

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Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

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Spironolactone reduced hair thickness and some testosterone levels in women with excessive hair growth.

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Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.

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43 citations, July 1984 in “Clinical and Experimental Dermatology”

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

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72 citations, December 1983 in “Journal of Investigative Dermatology”

Minoxidil helps hair cells live longer and grow longer.

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Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.

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Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

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The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.

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A woman regrew her hair significantly using a corticosteroid cream with a plastic cover.

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