Search

for
Search:

Glossary Topical Immunotherapy

deliberately triggers skin immune response to promote hair regrowth

Topical immunotherapy, also known as contact immunotherapy, is a treatment method used primarily for conditions like alopecia areata, where an immune response is deliberately triggered on the skin to promote hair regrowth. This is typically achieved by applying a chemical agent, such as diphencyprone (DPCP), to the affected area, causing a mild allergic reaction that can stimulate hair follicles and potentially lead to hair regrowth.

Related Terms

Research

5 / 1000+ results

research Topical immunotherapy in alopecia areata

45 citations , January 2010 in “International journal of trichology”

This review examines topical immunotherapy for severe alopecia areata, noting that diphencyprone and squaric acid dibutylester are non-mutagenic options with similar efficacy but different practical considerations, and reports no new clinical results.

research Seventeen Cases of Alopecia Areata: Combination of SADBE Topical Immunotherapy with Other Therapies

36 citations , October 2002 in “The Journal of Dermatology”

This study suggests that combining topical squaric acid dibutylester with other therapies may improve hair regrowth in patients with alopecia areata unresponsive to topical therapy alone.

research Topical immunotherapy of severe alopecia areata with diphenylcyclopropenone (DPCP): experience in an Iranian population

36 citations , May 2005 in “BMC dermatology”

This study found that topical diphenylcyclopropenone was effective in treating severe alopecia areata but had a high relapse rate and was often accompanied by side effects like eczema and lymphadenopathy.

research TOPICAL IMMUNOTHERAPY IN DERMATOLOGY

22 citations , March 1999 in “International Journal of Clinical Practice”

This review discusses the use of topical immunotherapy for severe alopecia areata and resistant viral warts, highlighting diphencyprone's advantages and the need for careful handling to avoid staff sensitisation; it reports no new clinical results.

research Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update

20 citations , March 2021 in “Drug design, development and therapy”

This review summarizes the pharmacology, mechanisms, and clinical efficacy of topical immunotherapy for alopecia areata but reports no new clinical results.

View more "topical immunotherapy" in research →

Community Join

5 / 1000+ results

community Desensitize Follicle Sensitivity to DHT?

12 upvotes 1 month ago

Hair follicles cannot be desensitized to DHT like allergies; treatments focus on reducing DHT levels or blocking its effects using methods like finasteride, GT20029, or PROTACs. Topical treatments like ceterizine and BPA application are also mentioned.

community Topical minoxidil routine and shampooing frequency

4 upvotes 1 week ago

The user applies 10% minoxidil nightly, takes 1mg finasteride, multivitamins, and a hair growth serum, and is concerned about over-washing hair with dermatologist-recommended shampoo. It is suggested to shampoo every other day and rinse with water on alternate days unless otherwise advised by a dermatologist.

community Topical min 13 months and oral fin 6 months, progress

11 upvotes 1 week ago

The user has been using topical minoxidil for 13 months and oral finasteride for 6 months to address hair loss after a hair transplant. They plan to switch to oral minoxidil for better results and occasionally use topical minoxidil and microneedling.

community F23 does Topical Min work on vellus hairs?

in Female 72 upvotes 1 week ago

Topical minoxidil 5% may help turn vellus hairs into normal-looking hairs, but results can vary, especially on the temples. The user stopped testosterone injections and finasteride, which may have affected hair recovery.

community Topical dutasteride + minox + oral fin 1mg/day

7 upvotes 1 week ago

The conversation discusses hair regrowth using topical dutasteride, minoxidil, and oral finasteride 1mg/day. The user reports seeing new hair growth.

View more "topical immunotherapy" in community →

Learn

5 / 26 results

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Bicalutamide

Is topical bicalutamide a safer alternative to finasteride? There is no published human trial of topical bicalutamide for hair loss, and no licensed topical product exists, so it cannot be called safer than finasteride — or shown to work at all. Oral finasteride has decades of trial data with a documented side-effect profile, and topical finasteride has a phase III trial behind it.

learn Rapamycin

Does topical rapamycin actually help reactivate dormant hair follicles? No study in living people has shown that topical rapamycin reactivates hair follicles; the evidence is from mice and cultured follicles.

View more "topical immunotherapy" in learn →

Clinics

1 / 1 results

Hair Loss Treatments
Immunotherapy Regenerative Medicine - Stem Cell ClinicPuerto Vallarta, Jalisco · MX

Experts

— no results

Try a deeper search in experts →