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    GlossaryTopical Immunotherapy

    deliberately triggers skin immune response to promote hair regrowth

    Topical immunotherapy, also known as contact immunotherapy, is a treatment method used primarily for conditions like alopecia areata, where an immune response is deliberately triggered on the skin to promote hair regrowth. This is typically achieved by applying a chemical agent, such as diphencyprone (DPCP), to the affected area, causing a mild allergic reaction that can stimulate hair follicles and potentially lead to hair regrowth.

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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Roughly one year on finasteride

      in Progress Pictures  513 upvotes 1 year ago
      The conversation is about someone's positive experience with 0.5 mg of finasteride daily for hair loss, noting potential contributions from vitamins and health improvements. Side effects and observations from others include watery semen and questions about hair regrowth and shedding phases.

      community Topical Min and fin usage after 7 months

      in Progress Pictures  12 upvotes 3 days ago
      The user had a hair transplant in December 2024 and started using topical minoxidil and finasteride in March 2025, along with dermarolling and multivitamins. They are experiencing increased hair shedding and are questioning if it's the "dread shed" phase.

      community Topical dutasteride is superior to oral finasteride

      in Research/Science  84 upvotes 3 days ago
      Topical dutasteride is more effective than oral finasteride for male pattern hair loss, with fewer side effects. Some prefer oral treatments for convenience, while others use topical solutions like minoxidil and dutasteride, sometimes with microneedling, for better results.

      community Topical Finasteride Gel 1% after 4 months — problems

      in Finasteride  156 upvotes 5 days ago
      The user experienced hair thinning due to a testosterone spike and used a minoxidil solution and topical finasteride gel. After four months, the gel caused side effects without improving hair thinning, leading to questions about continuing or adjusting the treatment.