Dapsone Versus Topical Immunotherapy in Alopecia Areata

August 1995 in “ British Journal of Dermatology ”

H. M. J. van Baar, C.J.M. van der Vleuten, P.C.M. KERKHOF

TLDR Topical immunotherapy is more effective than dapsone for treating severe alopecia areata.

In a study involving 27 patients with severe alopecia areata, dapsone treatment over an average of 10 months was found to be significantly less effective than long-term topical immunotherapy. The rate of hair regrowth in patients treated with dapsone was similar to the rate of spontaneous hair regrowth documented in existing literature.

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Research cited in this study

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research Evaluation of Oral Minoxidil in the Treatment of Alopecia Areata

34 citations , November 1987 in “Archives of Dermatology”

Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.

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54 citations , March 1987 in “Journal of The American Academy of Dermatology”

3% topical minoxidil effectively treats extensive alopecia areata with few side effects.

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122 citations , November 1984 in “Journal of the American Academy of Dermatology”

No single treatment is consistently effective for alopecia areata, and more research is needed.

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54 citations , August 1981 in “British Journal of Dermatology”

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research Large Doses of Glucocorticoid in the Treatment of Alopecia Areata

80 citations , November 1975 in “Acta dermato-venereologica”

Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.

research Treatment of Alopecia Areata With Steroid Solution

30 citations , December 1972 in “Archives of dermatology”

The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

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