34 citations
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November 1987 in “Archives of Dermatology” This study found that oral minoxidil showed limited cosmetic effectiveness in treating severe alopecia areata, with only 18% of patients experiencing a noticeable response.
54 citations
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March 1987 in “Journal of The American Academy of Dermatology” In this study, 3% topical minoxidil showed some efficacy in hair regrowth for patients with extensive alopecia areata, especially those with less than total scalp hair loss, but did not lead to complete remission.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.
54 citations
,
August 1981 in “British Journal of Dermatology” This study found that patients with alopecia areata had significantly lower T cell numbers and reduced lymphocyte responses compared to healthy controls, correlated with hair loss severity and presence of antithyroid antibodies.
80 citations
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November 1975 in “Acta dermato-venereologica” This study found that while some patients with severe alopecia areata responded to high-dose prednisolone, the response was inconsistent and the therapy's risks prevent recommending it for general use.
30 citations
,
December 1972 in “Archives of dermatology” This report examines efforts to enhance the efficacy of topical steroids for alopecia areata using penetration-enhancing vehicles and exceptionally high concentrations, noting systemic steroids often lead to relapses and toxicity.