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Glossary Topical Treatments

medications applied directly to the skin or scalp

Topical treatments, also known as topical agents or topical medications, are medications applied directly to a specific area of the skin or scalp to treat localized conditions. These treatments can include creams, gels, ointments, and lotions, and are commonly used for conditions like alopecia, psoriasis, and eczema, delivering active ingredients directly to the affected area to minimize systemic side effects.

Related Terms

Research

5 / 1000+ results

research Nanoparticles for Topical Application in the Treatment of Skin Dysfunctions—An Overview of Dermo-Cosmetic and Dermatological Products

122 citations , December 2022 in “International Journal of Molecular Sciences”

In this review, researchers discussed recent advances in nanotechnology for topical skin applications, highlighting how nanocarriers enhance skin penetration and targeting in treatments for diseases like melanoma and psoriasis, while acknowledging that the penetration mechanisms and health impacts of nanoparticles remain not fully understood.

research Onion Juice (Allium cepa L.), A New Topical Treatment for Alopecia Areata

95 citations , June 2002 in “The Journal of Dermatology”

In this study, using topical crude onion juice significantly improved hair regrowth in patients with patchy alopecia areata compared to tap water.

research Vitiligo as a Reaction to Topical Treatment with Diphencyprone

55 citations , January 1988 in “Dermatology”

This study observed that 6.7% of patients treated with diphencyprone for alopecia areata developed vitiligo, with varying patterns and improvements noted among cases.

research Topical Treatment of Alopecia Areata

50 citations , July 1981 in “Archives of Dermatology”

This study found that applying dinitrochlorobenzene (DNCB), a contact allergen, led to hair regrowth in patients with alopecia areata, while croton oil did not have the same effect.

research Treatment of alopecia universalis with topical Janus kinase inhibitors – a double blind, placebo, and active controlled pilot study

49 citations , August 2018 in “International Journal of Dermatology”

In this phase I study, partial hair regrowth was observed in patients with alopecia universalis using topical JAK inhibitors, though more research is needed to confirm potential as a treatment alternative to clobetasol.

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Community Join

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community Topical Treatment Progress

in Journals / Progress Pictures 53 upvotes 6 months ago

The user reported healthier, firmer, and thicker hair follicles with minimal regrowth at the front after using Regenera Activa, topical finasteride, minoxidil, tretinoin, caffeine solution, and vitamin D supplements. Hair loss has stabilized with no side effects.

community Topical Treatments and how would they work in a single compound

in Treatments 46 upvotes 6 months ago

A topical treatment called 1961, containing multiple products, is discussed for its compatibility with finasteride. It is suggested that 1961 does not negatively affect finasteride's effectiveness and may even enhance its absorption.

community Topical foam 5% Min, Vitamin B12, and Vitamin D treatment since July

in Progress Pictures 26 upvotes 10 months ago

The conversation discusses hair loss treatments, specifically using 5% minoxidil foam, Vitamin B12, and Vitamin D, with suggestions to add oral finasteride and minoxidil for better results. Concerns about side effects, particularly from finasteride, and the need for a DHT blocker are also highlighted.

community Topical ashwaganda as a treatment?

3 upvotes 2 years ago

Topical ashwagandha is discussed as a potential hair loss treatment. Minoxidil, finasteride, and RU58841 are also mentioned as treatments.

community Topical caffeine as an adjunct treatment. I think this should be considered.

4 upvotes 3 years ago

Topical caffeine is suggested as a beneficial adjunct treatment for hair growth due to its anti-fibrotic, anti-inflammatory, antioxidant, and other properties. There is skepticism about its effectiveness, especially at low concentrations like in Alpecin liquid.

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Learn

10 / 26 results

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Small, short trials suggest topical vitamin D analogues such as calcipotriol may help some people with mild patchy alopecia areata. There is no trial evidence that they help pattern hair loss.

learn Microneedling

Can microneedling make topical treatments like minoxidil work better? Small trials report more hair growth when microneedling is added to minoxidil, but the evidence is low quality, and the FDA has not cleared any microneedling device for hair loss or for use with minoxidil.

learn Vascular Endothelial Growth Factor

Is Vascular Endothelial Growth Factor (VEGF) available as a topical treatment, or is it only stimulated indirectly? VEGF is not available as a topical treatment for hair loss.

learn Verteporfin

Is Verteporfin used as a topical treatment, injection, or oral medication for hair loss? Verteporfin is an intravenous drug approved only for an eye condition; it is not approved for hair loss in any form. In the few published hair reports it was injected into the scalp alongside surgical wounding — unverified case reports of one and two patients, not trial evidence.

learn Osteopontin

Is Osteopontin more effective in topical treatments or oral supplements for hair loss? Neither route has been tested: there is no published human trial of topical or oral osteopontin for hair loss. The evidence is preclinical, and it points both ways — injected osteopontin promoted hair growth in mice, while an osteopontin-derived peptide suppressed growth in human scalp tissue and its authors proposed it for unwanted hair.