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Verteporfin

Light-activated eye drug being studied for scarring

Verteporfin, a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 689 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.

Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

Research 10

  1. Inhibition of the Hippo pathway by verteporfin reduces the proliferation and stemness of rat hair follicle neural crest stem cells under hypoxiaFASEB BioAdvances · 2025 · 2 citations
  2. Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancerBritish Journal of Cancer · 2014 · 399 citations · not about hair
  3. GUIDELINES FOR USING VERTEPORFIN (VISUDYNE®) IN PHOTODYNAMIC THERAPY TO TREAT CHOROIDAL NEOVASCULARIZATION DUE TO AGE-RELATED MACULAR DEGENERATION AND OTHER CAUSESRetina · 2002 · 246 citations · not about hair
  4. Verteporfin Therapy Combined with Intravitreal Triamcinolone in All Types of Choroidal Neovascularization due to Age-Related Macular DegenerationOphthalmology · 2005 · 148 citations · not about hair
  5. In vitro and in vivo activities of verteporfin-loaded nanoparticlesJournal of Controlled Release · 2005 · 95 citations · not about hair
  6. Clinical Pharmacokinetics of VerteporfinThe Journal of Clinical Pharmacology · 2002 · 91 citations · not about hair
  7. Hyaluronic acid-modified and verteporfin-loaded polylactic acid nanogels promote scarless wound healing by accelerating wound re-epithelialization and controlling scar formationJournal of Nanobiotechnology · 2023 · 57 citations · not about hair
  8. VerteporfinDrugs · 2003 · 52 citations · not about hair
  9. Monitoring Photoproduct Formation and Photobleaching by Fluorescence Spectroscopy Has the Potential to Improve PDT Dosimetry with a Verteporfin-like Photosensitizer¶Photochemistry and Photobiology · 2002 · 51 citations · not about hair
  10. Disparity between prostate tumor interior versus peripheral vasculature in response to verteporfin‐mediated vascular‐targeting therapyInternational Journal of Cancer · 2008 · 48 citations · not about hair
All on OpenAlex →

Posts 20

  1. Now That PP405 Hype is Gone What is Everyone Coping with as the Next Cure?Reddit · 1 Aug 2026
  2. Holy shit. Verteporfin may actually be the cureReddit · 9 Nov 2023
  3. Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!Reddit · 10 Mar 2026
  4. Microneedling with VerteporfinReddit · 21 May 2022
  5. PP405: Regrows Hair In 8 Weeks. Is This The Miracle Cure?Reddit · 1 Feb 2026
  6. Dr. Bloxham's Verteporfin TrialReddit · 27 Jul 2023
  7. Reduced libido + almost no morning erections after 1.5 years of topical finasteride + minoxidil — should I stop finasteride?Reddit · 11 Sept 2026
  8. About Verteporfin but not about hairReddit · 16 Nov 2023
  9. Tressless When They See Verteporfin ResultsReddit · 11 Nov 2023
  10. new update (with pics) on dr. barghouthi verteporfin trialReddit · 31 Mar 2023
  11. I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.Reddit · 25 Dec 2024
  12. So How Exactly Does Verteporfin Work?Reddit · 3 Nov 2022
  13. Verteporfin was so hyped but noone is talking about it nowReddit · 19 Mar 2024
  14. Dr. Bloxham Final verteporfin updateReddit · 13 Nov 2024
  15. Anyone use Verteporfin with their hair transplant yet?Reddit · 18 Oct 2021
  16. *UPDATE Verteporfin HAIR REGENERATION Human Trials ITS WORKING!Reddit · 24 Aug 2022
  17. Verteporfin day 119 update - donor hair regeneration human trialReddit · 16 Oct 2022
  18. Thoughts on my plan to keep my hair forever.Reddit · 6 Apr 2022
  19. Would you still need to be on finasteride if Verteporfin becomes widely used?Reddit · 11 Nov 2023
  20. Fin nuked my libido to below zeroReddit · 10 Sept 2026
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